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Vasospastic (Prinzmetal) Angina: Provocation Testing and Treatment

…vasoconstriction of one or more coronary arteries. Epicardial spasm produces a reversible functional occlusion and usually causes transmural ischaemia. The resulting abnormalities in left ventricular…

🟠 Nitroprusside

…toxicity is suspected. Adverse effects • Nausea. Vomiting. Agitation. Muscle spasm. Sweating. Flushing. • Prolonged high dose use may cause thiocyanate and cyanide toxicity . Nitroprusside is metabolized…

Type 2 Myocardial Infarction: Mechanisms and Management

…include fixed coronary atherosclerosis without plaque rupture, coronary artery spasm, coronary microvascular dysfunction (encompassing endothelial dysfunction, smooth muscle cell dysfunction, and dysregulation of sympathetic innervation)…

Myocardial Injury Versus Infarction: Interpreting Troponin Elevation

…of myocardial injury Important causes include: Mechanism or clinical setting Examples Acute coronary atherothrombosis Plaque disruption or erosion with thrombosis Reduced myocardial perfusion Coronary spasm…

Statin Intolerance and Statin-Associated Muscle Symptoms

…is statin associated muscle symptoms (SAMS). These range from diffuse myalgia with a normal CK and no functional impairment to myositis with muscle inflammation and…

Post-Infarction Mechanical Complications: Ventricular Septal, Free-Wall, and Papillary Muscle Rupture

…Ventricular free wall rupture, producing haemopericardium and cardiac tamponade. Papillary muscle rupture, producing acute severe mitral regurgitation (MR). These complications result from transmural myocardial necrosis…

Reduction of dislocations

Procedurer A dislocation is reduced with muscle relaxation, not with force. The methods that work best exploit time, gravity and slow movement; those that fail…

Cardiac troponin I (TnI) and T (TnT): Interpretation and evaluation in acute coronary syndromes

ECG Troponin is a protein complex expressed in cardiac and skeletal muscle. The complex consists of troponin I (TnI) , troponin C (TnC) and troponin T…

Anthropometric measurements

…population measure that performs poorly at the level of the individual: it does not distinguish muscle from fat and takes no account of fat distribution…

Renal parameters

…halve before the creatinine leaves the reference range, because the relationship is hyperbolic. In people with a low muscle mass — the elderly, the undernourished, amputees…

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