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Heart Failure With Preserved Ejection Fraction: Diagnosis and Treatment

…are elevated. The syndrome is therefore defined by symptoms and signs of congestion or impaired cardiac performance rather than by ejection fraction alone. Heart failure…

Evaluation of exercise stress test: ECG, symptoms, blood pressure, heart rate, performance

…increased sweating, and muscle fatigue. Although this is a subjective measure, it provides a fairly good estimate of the actual workload. The perceived exertion may…

Edrophonium test

…and monitors, one who assesses and documents muscle function. Define the outcome measure before the test. Measure the size of the ptosis in millimetres, the…

Digoxin: Dosing, Therapeutic Range and Toxicity Management

…AV nodal refractoriness. Its electrophysiologic effects on the His Purkinje system and ventricular muscle are minimal, except in cases of toxic concentrations. In most patients…

Statin Intolerance and Statin-Associated Muscle Symptoms

…soreness Weakness, often perceived or functional Predominant involvement of large proximal muscle groups Symptoms commonly begin within 4–6 weeks of starting treatment. They generally…

Post-Infarction Mechanical Complications: Ventricular Septal, Free-Wall, and Papillary Muscle Rupture

…muscle rupture causes abrupt severe MR. Its typical presentation is: Sudden severe dyspnoea. Acute pulmonary oedema. Hypotension. Progressive heart failure. Cardiogenic shock. Complete transection of…

Reduction of dislocations

…determine afterwards whether a nerve injury was caused by the injury or by the treatment. Indications A clinically or radiologically confirmed dislocation of the shoulder…

Cardiac troponin I (TnI) and T (TnT): Interpretation and evaluation in acute coronary syndromes

ECG Troponin is a protein complex expressed in cardiac and skeletal muscle. The complex consists of troponin I (TnI) , troponin C (TnC) and troponin T…

Anthropometric measurements

…BMI of 23 and obesity from 27.5, because cardiometabolic risk appears at a lower BMI. BMI is misleading in athletes with a large muscle…

Renal parameters

…with a low muscle mass — the elderly, the undernourished, amputees, patients with hepatic cirrhosis — creatinine based eGFR substantially overestimates renal function. Staging of chronic kidney…

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