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Heart Failure With Preserved Ejection Fraction: Diagnosis and Treatment

…are elevated. The syndrome is therefore defined by symptoms and signs of congestion or impaired cardiac performance rather than by ejection fraction alone. Heart failure…

Evaluation of exercise stress test: ECG, symptoms, blood pressure, heart rate, performance

…increased sweating, and muscle fatigue. Although this is a subjective measure, it provides a fairly good estimate of the actual workload. The perceived exertion may…

Edrophonium test

…obstruction of the bowel or the urinary tract. Marked bradycardia, sick sinus syndrome or high grade AV block without pacemaker protection. Asthma and other marked…

Digoxin: Dosing, Therapeutic Range and Toxicity Management

…AV nodal refractoriness. Its electrophysiologic effects on the His Purkinje system and ventricular muscle are minimal, except in cases of toxic concentrations. In most patients…

Statin Intolerance and Statin-Associated Muscle Symptoms

…soreness Weakness, often perceived or functional Predominant involvement of large proximal muscle groups Symptoms commonly begin within 4–6 weeks of starting treatment. They generally…

Post-Infarction Mechanical Complications: Ventricular Septal, Free-Wall, and Papillary Muscle Rupture

…muscle rupture causes abrupt severe MR. Its typical presentation is: Sudden severe dyspnoea. Acute pulmonary oedema. Hypotension. Progressive heart failure. Cardiogenic shock. Complete transection of…

Reduction of dislocations

…determine afterwards whether a nerve injury was caused by the injury or by the treatment. Indications A clinically or radiologically confirmed dislocation of the shoulder…

Cardiac troponin I (TnI) and T (TnT): Interpretation and evaluation in acute coronary syndromes

ECG Troponin is a protein complex expressed in cardiac and skeletal muscle. The complex consists of troponin I (TnI) , troponin C (TnC) and troponin T…

Anthropometric measurements

…account of fat distribution. Waist circumference and the waist–hip ratio predict cardiometabolic risk better, particularly at a BMI between 25 and 35. Body mass…

Renal parameters

…with a low muscle mass — the elderly, the undernourished, amputees, patients with hepatic cirrhosis — creatinine based eGFR substantially overestimates renal function. Staging of chronic kidney…

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