12 träffar

DrugNon-selective COX inhibitor, propionic acid derivative
Ibuprofen

…cardiovascular risk at a low dose. A short half-life of around 2 hours means the effect arrives and resolves quickly, which is an advantage:…

DrugLong-acting basal insulin
Insulin glargine

Lantus Abasaglar Toujeo Semglee Long-acting basal insulin The basal insulin that covers the basal insulin requirement between meals and overnight, with a largely flat…

DrugRecombinant tissue plasminogen activator (rt-PA)
Alteplase

…mg — and confusing them is the most common serious error. The short half-life means the effect cannot be reversed once the dose is given.

DrugDirect factor Xa inhibitor
Apixaban

…dosing and no routine monitoring. Lower risk of intracranial haemorrhage than warfarin — but the short half-life means a missed dose has consequences within hours.

DrugNatural penicillin for parenteral use
Benzylpenicillin

…Time-dependent killing means that the dosing interval matters more than the size of any individual dose — four doses are preferable to two large ones…

DrugHigh-potency glucocorticoid with long duration
Betamethasone

…receive a full steroid dose without an injection, and the long biological duration means a single dose suffices. Potency is approximately 25 times that of…

DrugSynthetic vasopressin analogue (V2 agonist)
Desmopressin

…Selectivity for the V2 receptor means it lacks the vasoconstrictive effect of vasopressin. The danger is not the drug itself but the fluid the patient…

DrugSynthetic catecholamine, β₁-agonist (inotropy)
Dobutamine

…when the problem is the pump and not vascular tone. Strong β₁ effect with marked β₂ effect means that stroke volume increases while systemic vascular…

DrugVascular-selective dihydropyridine calcium channel blocker
Felodipine

…hypertension and stable angina. The selectivity for vascular smooth muscle means felodipine lacks the nodal effects of verapamil and diltiazem — no bradycardia, no AV block…

DrugRapid-acting insulin analogue
Insulin aspart

…is a few minutes, which makes the infusion fully controllable but also means the effect ceases within minutes if the drip stops. Always clearly distinguish…

DrugEndogenous purine nucleoside, AV-nodal blocking agent
Adenosine

…that do not — atrial flutter and atrial tachycardia are unmasked when the ventricular response is slowed. The half-life of a few seconds means both…

DrugConcentrated carbohydrate solution for acute hypoglycaemia
Glucose (concentrated, IV)

…is available. The effect arrives within a minute but is also short-lived — the bolus reverses unconsciousness but does not treat the cause. What determines…