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🟠 Ticagrelor (Brilinta, Brilique)

…ritonavir, and atazanavir) can lead to a significant increase in exposure to ticagrelor. Dosage: Acute Coronary Syndromes Treatment with Ticagrelor should start with a loading…

Exercise Electrocardiographic Testing: Indications, Limitations and Interpretation

…usually on a treadmill, while symptoms, a 12 lead ECG, heart rate and blood pressure are monitored. The test is generally symptom limited and is…

Heart Failure With Preserved Ejection Fraction: Diagnosis and Treatment

…female sex, atrial fibrillation (AF), chronic kidney disease (CKD), and multiple non cardiovascular conditions are frequent features. A proposed disease pathway involves systemic and coronary…

Aortic regurgitation

…with increasing myocardial load (and hence oxygen demand). The most common causes of acute aortic regurgitation are aortic dissection , endocarditis and trauma . Chronic aortic regurgitation…

Inotropes and vasopressors: doses, indications, contraindications and effects

…receptors and induces vasodilatation in the coronary, renal, cerebral and mesenteric vessels. Few Dopamine — intermediate dose Cardiogenic shock. Vasodilatory shock. Heart failure, acute or chronic…

Heart Failure with Preserved Ejection Fraction (HFpEF)

…hypertension, diabetes) induce a chronic, systemic proinflammatory state. This circulating inflammation leads to coronary microvascular endothelial dysfunction, characterized by the upregulation of adhesion molecules (e…

Tachycardia induced cardiomyopathy

…This type of cardiomyopathy, referred to as tachycardia induced cardiomyopathy , can be caused by any tachyarrhythmia leading to prolonged periods of rapid ventricular rate (Table…

Dilated Cardiomyopathy (DCM): Definition, Types, Diagnostics & Treatment

…following cardiomyopathies lead to dilation of the ventricle: Dilated cardiomyopathy (DCM) Idiopathic or genetic . Ischemic cardiomyopathy Alcoholic cardiomyopathy Diabetic cardiomyopathy Takotsubo cardiomyopathy Tachycardia induced cardiomyopathy…

Vasospastic (Prinzmetal) Angina: Provocation Testing and Treatment

…spasm produces a reversible functional occlusion and usually causes transmural ischaemia. The resulting abnormalities in left ventricular function may lead to myocardial infarction, ventricular tachycardia…

Exercise stress test on cycle ergometer

…equipment Cycle ergometer with a braked, workload controlled resistance; 12 lead ECG with continuous recording; automated or manual blood pressure measurement. Resuscitation trolley with defibrillator…

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