…demyelination HINTS plus by a trained examiner if nystagmus is present, neurological examination, gait and truncal stability Acute balance syndrome Acute persistent unsteadiness or ataxia…

…4. Where possible, take the plasma osmolality, urine osmolality and urine sodium before treatment. 5. With severe symptoms: give hypertonic saline immediately. Do not wait…

…walking or a slow gait without describing classic claudication. In older adults, approximately 40% are asymptomatic, 50% report atypical leg symptoms and fewer than 10…

…M. R. (2017). Beta blocker therapy for long QT syndrome and catecholaminergic polymorphic ventricular tachycardia: Are all beta blockers equivalent? Heart Rhythm , 14(1), e41…

…M. R. (2017). Beta blocker therapy for long QT syndrome and catecholaminergic polymorphic ventricular tachycardia: Are all beta blockers equivalent? Heart Rhythm, 14(1), e41…

… consider inotropic support Persistent congestion despite initial therapy Increase diuretic dose and/or combine diuretic classes Diuretic resistance or end stage renal failure Consider renal…

…binding to the LDL receptor. Gain of function variants in PCSK9, which reduce recycling and surface availability of hepatic LDL receptors. Rare biallelic variants in…

…the rationale for therapeutic inhibition. Gain of function PCSK9 mutations are associated with familial hypercholesterolaemia (FH) and premature coronary heart disease, whereas loss of function…

…axial length of SV) and sweep speed is set to 50 mm/s to 100 mm/s (Figure 1). Gain and filter should be minimized…

…gain. This amplifies the incoming (reflected) ultrasound waves such that each object appears whiter on the image. Increasing gain excessively results in lower resolution and…

…the need for ventilatory support . At the same time, exacerbation is a clinical syndromic diagnosis, not a sufficient explanation for all acute dyspnoea in a…

…Set the filter: a frequency range of about 15–40 Hz , and adjust the gain so that the atrial deflections are clear without clipping. 4…

…Doppler alignment may skew results. Assumptions : Formulas assume laminar flow and circular LVOT/RVOT geometry, which may not hold in all patients. Error in Calculation …

…and vice versa (i.e the frequency is reduced when studying distant objects). These concepts have been discussed in detail previously. The gain is regulated…