…Accurate risk stratification is pivotal in guiding therapeutic decisions for LQTS patients. Traditional assessment methods have focused on genotype and QTc interval prolongation. In 2018…

…Accurate risk stratification is pivotal in guiding therapeutic decisions for LQTS patients. Traditional assessment methods have focused on genotype and QTc interval prolongation. In 2018…

…Assessment should integrate the history, physical examination, laboratory data and diagnostic testing. Examination for congestion Useful bedside indicators of persistent or improving congestion include: J

…or brainstem infarction, haemorrhage, drug toxicity, demyelination HINTS plus by a trained examiner if nystagmus is present, neurological examination, gait and truncal stability Acute balance…

…stroke, meningitis and a postictal state. 3. Check a repeat plasma sodium if the result is unexpected or does not fit the clinical picture. 4…

…impaired walking or a slow gait without describing classic claudication. In older adults, approximately 40% are asymptomatic, 50% report atypical leg symptoms and fewer than…

…binding to the LDL receptor. Gain of function variants in PCSK9, which reduce recycling and surface availability of hepatic LDL receptors. Rare biallelic variants in…

…the rationale for therapeutic inhibition. Gain of function PCSK9 mutations are associated with familial hypercholesterolaemia (FH) and premature coronary heart disease, whereas loss of function…

[calc_shunt] Calculating Shunt Fraction (Qp/Qs) Using Echocardiography: A Guide to Methods and Clinical Relevance The shunt fraction (Qp/Qs) is a critical hemodynamic…

…Set the filter: a frequency range of about 15–40 Hz , and adjust the gain so that the atrial deflections are clear without clipping. 4…

…Initial assessment Confirm that the presentation fits an exacerbation A COPD exacerbation is an acute or subacute worsening of dyspnoea, cough and sputum in particular…

…Gain and filter should be minimized in order to obtain optimal images. The pulsed Doppler beam can be positioned using color Doppler (to visualize the…

…gain applied to incoming sound waves. This is done using gain control or time gain compensation (TGC) . Figure 1. TGC (time gain compensation) and gain…

…of image quality. The ultrasound transducer is held at the tip, using the thumb and the forefinger, while remaining fingers stabilize the grip. The transducer…