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Immediate Management of Type A and Type B Aortic Dissection

…alongside intramural haematoma, penetrating atherosclerotic ulcer, aortic pseudoaneurysm and traumatic aortic injury. In classic dissection, an intimal tear permits blood to enter the diseased aortic…

Acute vertigo: quick reference for HINTS and differential diagnosis

…examination, ECG, selective vascular imaging Traumatic or toxic syndrome Onset after trauma, a change in medication or an exposure Concussion, temporal bone injury, dissection, aminoglycoside…

Lumbar puncture

…with a reduced level of consciousness, focal neurological signs or seizures — because the delay costs more than the scan contributes. Only clinical signs of herniation…

Atherosclerosis: Pathogenesis from Fatty Streak to Plaque Rupture

…cell recruitment, extracellular matrix remodelling, and thrombosis interact to produce focal arterial lesions. Although epicardial coronary arteries are a major site of disease, atherosclerosis is…

Acute Aortic Syndromes: Intramural Haematoma and Penetrating Atherosclerotic Ulcer

…subclavian artery. Penetrating atherosclerotic ulcer PAU is focal ulceration of an atherosclerotic plaque that penetrates through the internal elastic lamina into the media. The lesion…

Atrial Flutter: Mechanisms, ECG Recognition and Management

…Conversely, certain macroreentrant atrial tachycardias (MRATs) that traverse protected anatomical areas may display a focal atrial tachycardia pattern on the ECG, characterized by discrete P…

Carotid Artery Disease: Screening, Medical Therapy and Revascularisation

…and the broader atherosclerotic burden. Clinical Presentation and Symptoms Asymptomatic disease Many patients with carotid stenosis have no focal neurological symptoms. Asymptomatic disease may be…

Percutaneous Coronary Intervention Versus Coronary Artery Bypass Grafting in Multivessel Coronary Artery Disease

…within the broader framework of guideline directed medical therapy and secondary prevention. PCI treats focal stenotic segments, whereas CABG provides a bypass beyond diseased segments…

Acute exacerbation of COPD: quick reference

…on chronic hypercapnic respiratory failure Rapidly falling pH An urgent ventilatory problem Focal chest pain or unilaterally reduced breath sounds Consider pneumothorax New arrhythmia or…

Alcohol withdrawal and delirium tremens: quick reference

…Seizures later than this, focal seizures or status epilepticus should raise strong suspicion of another or an additional cause [1]. Delirium tremens most often begins…

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