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Familial and Genetic Screening in Premature Cardiovascular Disease

…medicine is the systematic assessment of relatives and other individuals who may carry an inherited predisposition to cardiovascular disease. It combines a structured family history…

Familial Hypercholesterolaemia: Diagnosis, Cascade Screening and Treatment

…multigenerational family history. The evaluation should establish: The magnitude of untreated LDL C elevation. The presence and age of onset of premature CAD or other…

Brugada syndrome: ECG, clinical features and management

…syndrome – appeared to be hereditary, since many patients reported a family history of the same symptoms and events. Perhaps the most distinguishing feature was the…

🟠 Adjusted aortic root dimension

…aorta, aortic arch) All individuals 60 mm (descending aorta) All individuals Risk factors : previous dissection, family history of dissection, severe aortic regurgitation or mitral regurgitation…

Dilated Cardiomyopathy (DCM): Definition, Types, Diagnostics & Treatment

…Other causes of ventricular dilation ( e.g ischemic cardiomyopathy) must be excluded before establishing a diagnosis of DCM. Patient characteristics, clinical features, family history and…

Carotid Artery Disease: Screening, Medical Therapy and Revascularisation

…or other atherosclerotic disease; diabetes and other cardiovascular risk factors; smoking, hypertension, hypercholesterolaemia, and sedentary behaviour; family history, particularly in the broader assessment of peripheral…

Approach to patients with chest pain: differential diagnoses, management & ECG

…these five conditions, there are numerous other causes of chest pain, but the other causes are either subacute or non acute. The history taking must…

Primary Aldosteronism: Screening and Management

…termed glucocorticoid remediable aldosteronism, and other familial forms associated with adrenal adenoma or bilateral adrenal hyperplasia. A family history is therefore important, particularly in patients…

Quiz: ECG in athletes

…to ECG interpretation 1. Which of the following ECG findings is typically considered a normal variant in asymptomatic athletes with no significant family history? A:…

Risk Factor Modification: The Evidence Base for Primary Prevention

…and alcohol consumption. Additional considerations include psychosocial stress, obstructive sleep apnoea, social determinants of health, air pollution, family history, ethnicity, and frailty. Primary prevention is…

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