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Familial Hypercholesterolaemia: Diagnosis, Cascade Screening and Treatment

…lipid testing showing severe hypercholesterolaemia. A personal history of premature CAD, cerebral vascular disease or peripheral vascular disease. A family history of premature myocardial infarction…

Lipoprotein(a): Measurement and Clinical Implications

…patients with familial hypercholesterolaemia or very high LDL cholesterol; people with a family history of premature cardiovascular disease; those with a family history of high…

Familial and Genetic Screening in Premature Cardiovascular Disease

…medicine is the systematic assessment of relatives and other individuals who may carry an inherited predisposition to cardiovascular disease. It combines a structured family history…

A Novel Familial Cardiac Arrhythmia Syndrome Identified Using ECG

…novel familial (autosomal dominant) cardiac syndrome. The underlying genetic abnormality is yet to be discovered. Diagnosis of this syndrome is based on ECG, family history…

Primary Aldosteronism: Screening and Management

…include familial hyperaldosteronism type 1, formerly termed glucocorticoid remediable aldosteronism, and other familial forms associated with adrenal adenoma or bilateral adrenal hyperplasia. A family history…

🟠 Adjusted aortic root dimension

…aorta, aortic arch) All individuals 60 mm (descending aorta) All individuals Risk factors : previous dissection, family history of dissection, severe aortic regurgitation or mitral regurgitation…

Quiz: ECG in athletes

…to ECG interpretation 1. Which of the following ECG findings is typically considered a normal variant in asymptomatic athletes with no significant family history? A:…

Dilated Cardiomyopathy (DCM): Definition, Types, Diagnostics & Treatment

…idiopathic or genetic dilation of the left ventricle . Patients with DCM typically develop heart failure early in life and a family history of heart failure…

Risk Factor Modification: The Evidence Base for Primary Prevention

…and alcohol consumption. Additional considerations include psychosocial stress, obstructive sleep apnoea, social determinants of health, air pollution, family history, ethnicity, and frailty. Primary prevention is…

Carotid Artery Disease: Screening, Medical Therapy and Revascularisation

… smoking, hypertension, hypercholesterolaemia, and sedentary behaviour; family history, particularly in the broader assessment of peripheral arterial and aortic disease; planned surgery, especially carotid endarterectomy (CEA…

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