11 träffar

DrugNon-selective β₁- and β₂-agonist without alpha effect
Isoprenaline

…vessels — completely without alpha effect. The result is that heart rate rises while systemic vascular resistance and diastolic blood pressure fall, so the drug raises…

DrugLinkosamid med proteinsynteshämmande effekt
🇸🇪 Clindamycin

…Två egenskaper motiverar preparatet: utmärkt penetration i ben, led och mjukdelar med nästan full biotillgänglighet peroralt, och en hämning av bakteriell proteinsyntes som stänger av…

DrugSelective dopamine-1 receptor agonist
Fenoldopam

…increases renal perfusion while blood pressure falls. A selective D1 agonist without alpha or beta effects, with onset within minutes and duration under one hour …

DrugKortverkande β₂-agonist (SABA)
🇸🇪 Salbutamol

…Airomir Buventol Easyhaler Salbutamol Teva Kortverkande β₂-agonist (SABA) Snabbaste sättet att öppna en trång luftväg — anslag inom minuter och full effekt inom en kvart…

DrugHigh-potency glucocorticoid with long duration
Betamethasone

…croup or a patient with an allergic reaction to receive a full steroid dose without an injection, and the long biological duration means a single…

DrugSynthetic catecholamine, β₁-agonist (inotropy)
Dobutamine

…the pump and not vascular tone. Strong β₁ effect with marked β₂ effect means that stroke volume increases while systemic vascular resistance falls at low…

DrugSGLT2 inhibitor
Empagliflozin

…EMPEROR-Reduced and EMPEROR-Preserved, and slowed renal function decline down to eGFR 20 in EMPA-KIDNEY. The glucose-lowering effect diminishes as eGFR falls…

DrugGabapentinoid, ligand to the α2δ subunit of voltage-gated calcium channels
Gabapentin

…so bioavailability falls as the dose rises and the dose–concentration relationship is non-linear. Hence the wide dose range and three-times-daily regimen…

DrugSpecific antidote to dabigatran, humanised Fab fragment
Idarucizumab

…than dabigatran binds to thrombin — in practice it never lets go. The effect is immediate and complete: unbound dabigatran in plasma falls by over 99…

DrugSyntetiskt tyroideahormon (T4)
🇸🇪 Levothyroxine

…att patienten tar tabletten rätt. Ung och hjärtfrisk patient kan starta på full substitutionsdos omkring 1,6 μg/kg, medan äldre och patienter med…

DrugFyrfaktorkoncentrat med faktor II, VII, IX och X
🇸🇪 Prothrombin complex concentrate

…och förstahandsval när warfarineffekt måste hävas omedelbart. Full effekt inom tio minuter och i en volym som en blödande patient tål, till skillnad från plasma…