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Non-ST Elevation Acute Myocardial Infarction (NSTEMI) and Unstable Angina

…linking). Concurrent activation of the coagulation cascade leads to thrombin generation and fibrin deposition, culminating in a partially or fully occlusive intraluminal thrombus [5] . ACS…

Contrast-Associated Acute Kidney Injury: Risk Assessment and Prevention

…the combined effects of contrast exposure and other ischaemic or nephrotoxic stresses. The kidney is particularly vulnerable to toxic injury because of its high blood…

Risk Factor Modification: The Evidence Base for Primary Prevention

…and duration of exposure to cardiovascular risk factors. Primary prevention Primary prevention targets people without clinical CVD who nevertheless have established risk factors or an…

Gynaecological examination and cervical smear

…permanent part of the programme and is widely used — a woman who does not attend for a gynaecological examination, or who prefers to take the…

Arterial Hypertension: Definition, Diagnosis and Out-of-Office Measurement

…central to diagnosis and long term management. Clinical presentation and symptoms The source material does not describe the typical symptoms or symptom burden of uncomplicated…

Poisoning: quick reference for antidotes and initial management

…needed. Intubate for a threatened airway, a marked risk of aspiration, or failure that is not rapidly reversed by an antidote B Respiratory rate, saturation…

Alcohol and Cardiovascular Disease

…women or five for men on one occasion. Pharmacokinetics and pathophysiology Approximately 95% of ingested ethanol undergoes hepatic metabolism. Alcohol dehydrogenase converts ethanol to acetaldehyde…

Vulnerable Plaque and Mechanisms of Acute Coronary Occlusion

…rupture Plaques prone to rupture characteristically contain a large lipid pool, numerous macrophages or foam cells, and a thin fibrous cap. Disruption of the cap…

Cardiac arrest in intoxication (poisoning)

…if suspected of toxin exposure. Gastrointestinal lavage is infrequently employed due to aspiration risks and inconclusive evidence. However, in cases of iron, lithium, or potassium…

Anaphylaxis: quick reference for emergency management

…after exposure to a known or probable allergen , even if skin symptoms are absent [1,4]. Typical warning symptoms are: hoarseness, stridor, swelling of the…

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