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Risk Factor Modification: The Evidence Base for Primary Prevention

…at increased risk and reducing exposure to established, modifiable determinants of cardiovascular disease. The principal targets include blood pressure, lipid abnormalities, diabetes and glycaemic status…

Coronary CT Angiography and CAD-RADS Reporting

…attenuation is expressed relative to water in Hounsfield units. Bone is highly attenuating, air has very low attenuation, and blood and myocardium have intermediate values…

Contrast-Associated Acute Kidney Injury: Risk Assessment and Prevention

Cardiology Nephrology Definition and terminology Contrast associated acute kidney injury is an acute deterioration in renal function occurring after exposure to iodinated contrast media, particularly…

Familial Hypercholesterolaemia: Diagnosis, Cascade Screening and Treatment

…higher in populations with a founder effect. HoFH is much rarer, affecting approximately 1 in 250,000–350,000 individuals. The lifelong exposure to high…

Poisoning: quick reference for antidotes and initial management

…external exposure A low Glasgow Coma Scale is not on its own an absolute indication for intubation. Assess ventilation, airway protection, the expected course and…

Anticoagulants: quick reference for dosing, renal adjustment and reversal

…stroke quick reference. Stopping the drug and forgetting to restart it after the procedure. Document the restart date in the medical record. Sources ESC Guidelines…

Physics of myocardial perfusion imaging (SPECT, PET): Radiotracers, perfusion, blood flow and viability

…other, producing two gamma photons emitted in opposite directions. PET scanners detect these gamma rays to construct images with high spatial and temporal resolution. PET…

LDL Cholesterol Targets Across Cardiovascular Risk Categories

…modest absolute reduction may be clinically important in individuals at high or very high risk. Prolonged exposure to lower LDL C concentrations is associated with…

Cardiovascular Prevention in the Very Elderly

…atrial fibrillation, and age related changes in left ventricular filling contribute to susceptibility. Heart failure with preserved ejection fraction is regarded as a multifactorial systemic…

Injection technique — intramuscular, subcutaneous and intradermal

…1. Expose the whole shoulder; rolling up a sleeve creates a constriction that distorts the anatomy and tempts the operator to inject too high. 2…

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