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Dual Antiplatelet Therapy Duration After Acute Coronary Syndromes and Elective Percutaneous Coronary Intervention

Myocardial ischemia and infarction Pharmacology & dosing Definition and pathophysiology Dual antiplatelet therapy (DAPT) is the combined use of aspirin and an oral P2Y12 receptor inhibitor…

De-escalation and Shortened Dual Antiplatelet Therapy in Patients at High Bleeding Risk

Myocardial ischemia and infarction Pharmacology & dosing Definition and pathophysiological rationale Dual antiplatelet therapy (DAPT) denotes treatment with aspirin plus a P2Y12 receptor inhibitor. In the…

Antiplatelet Therapy in Secondary Prevention After Myocardial Infarction

Myocardial ischemia and infarction Pharmacology & dosing Definition and pathophysiological basis Secondary prevention after myocardial infarction (MI) encompasses long term interventions intended to reduce recurrent infarction…

SGLT2 Inhibitors for Cardiovascular and Renal Protection

…the source material are canagliflozin, dapagliflozin and empagliflozin; sotagliflozin is a related dual SGLT1/SGLT2 inhibitor. SGLT2 is a high capacity, low affinity transporter situated…

Drug-Eluting Coronary Stents: Evolution, Evidence and Stent Choice

…need for emergency CABG. Metal only stents, now termed BMS, reduced restenosis compared with balloon angioplasty but did not eliminate it. Angiographic restenosis—defined in…

Percutaneous Coronary Intervention Versus Coronary Artery Bypass Grafting in Multivessel Coronary Artery Disease

…and treatment goals Diabetes, left ventricular function and other comorbidities Surgical risk and contraindications to prolonged dual antiplatelet therapy Patient preferences, local expertise and operator…

Incretins in Cardiometabolic Medicine: Leveraging GLP-1, GIP, and Glucagon Receptor Agonism for Cardiovascular Risk Reduction

…circumference, waist to hip ratio, or dual X ray absorptiometry are recommended to more accurately diagnose clinical obesity and assess cardiovascular risk. 4 Furthermore, ectopic…

The physiology of cardiopulmonary resuscitation (CPR)

…1). These recommendations are based on observational data ( Stiell et al, Idris et al, Duval et al ). Randomized clinical trials are lacking. Figure 1 . Left…

Arterial line

…easy to compress, with a dual collateral supply to the hand through the palmar arches and the lowest complication rate. The femoral artery is the…

Basic cardiac pacing, pacemaker functions and settings

…implanted pacemakers are dual chamber systems , meaning that two leads are used: one in the atrium and one in the ventricle. Dual chamber systems offer…

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