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Dual Antiplatelet Therapy Duration After Acute Coronary Syndromes and Elective Percutaneous Coronary Intervention

Myocardial ischemia and infarction Pharmacology & dosing Definition and pathophysiology Dual antiplatelet therapy (DAPT) is the combined use of aspirin and an oral P2Y12 receptor inhibitor…

De-escalation and Shortened Dual Antiplatelet Therapy in Patients at High Bleeding Risk

Myocardial ischemia and infarction Pharmacology & dosing Definition and pathophysiological rationale Dual antiplatelet therapy (DAPT) denotes treatment with aspirin plus a P2Y12 receptor inhibitor. In the…

SGLT2 Inhibitors for Cardiovascular and Renal Protection

…the source material are canagliflozin, dapagliflozin and empagliflozin; sotagliflozin is a related dual SGLT1/SGLT2 inhibitor. SGLT2 is a high capacity, low affinity transporter situated…

Antiplatelet Therapy in Secondary Prevention After Myocardial Infarction

…prasugrel, and ticagrelor. Combining aspirin with a P2Y12 inhibitor produces dual antiplatelet therapy (DAPT), while treatment with one antiplatelet drug constitutes single antiplatelet therapy (SAPT)…

Percutaneous Coronary Intervention Versus Coronary Artery Bypass Grafting in Multivessel Coronary Artery Disease

…and treatment goals Diabetes, left ventricular function and other comorbidities Surgical risk and contraindications to prolonged dual antiplatelet therapy Patient preferences, local expertise and operator…

Arterial line

…easy to compress, with a dual collateral supply to the hand through the palmar arches and the lowest complication rate. The femoral artery is the…

Drug-Eluting Coronary Stents: Evolution, Evidence and Stent Choice

…metallic scaffold without an antiproliferative coating. Their advantages historically included a shorter required duration of dual antiplatelet therapy (DAPT), which could be as brief as…

Incretins in Cardiometabolic Medicine: Leveraging GLP-1, GIP, and Glucagon Receptor Agonism for Cardiovascular Risk Reduction

…circumference, waist to hip ratio, or dual X ray absorptiometry are recommended to more accurately diagnose clinical obesity and assess cardiovascular risk. 4 Furthermore, ectopic…

Basic cardiac pacing, pacemaker functions and settings

…implanted pacemakers are dual chamber systems , meaning that two leads are used: one in the atrium and one in the ventricle. Dual chamber systems offer…

ECG in myocardial ischemia: ischemic changes in the ST segment & T-wave

…acute coronary syndromes. Subsequent chapters will deal with ST segment elevation myocardial infarction (STEMI) and non ST segment elevation myocardial infarction (Non STEMI, NSTEMI) in…

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