…Use of cannabis, electronic cigarettes or other inhaled products. Readiness to attempt cessation. Depression, schizophrenia, schizoaffective disorder, HIV infection or other circumstances that may affect…

…risk factor [2] . This change reflects robust evidence that female sex alone, in the absence of other comorbidities, does not significantly increase stroke risk. Conversely…

…Use of synchronized electric shock (i.e. a shock synchronized to the QRS complex). Typically used to treat atrial fibrillation, ventricular tachycardia, and other tachyarrhythmias…

…progressive, and highly complex lipid driven inflammatory disease of the arterial intima that serves as the fundamental pathophysiological substrate for acute coronary syndromes (ACS), including…

…a cerumen loop. Suction with Frazier tips of various sizes. A balloon catheter (a 5–6 Fr Fogarty or a Katz extractor). A local anaesthetic…

…proportion of painless or silent STEMIs is greater in patients with diabetes mellitus and increases with age. STEMI may present as sudden onset breathlessness. Other…

…newly detected for the first time, or newly developed during management of an acute illness. The clinical relationship between AF and acute deterioration is often…

…necrosis and troponin elevation due to mechanisms other than myocardial ischaemia. Acute myocardial injury may arise from conditions such as sepsis, myocarditis, or takotsubo syndrome…

…aldosterone levels. Clinical Presentation and Symptoms In the management of heart failure, digoxin improves hemodynamics without increasing heart rate or decreasing blood pressure, making it…

…of neoatherosclerosis helps explain why ISR and other stent related events may arise well after the initial intervention. Mechanical mechanisms Mechanical abnormalities may initiate or…

…magnitude of untreated LDL C elevation. The presence and age of onset of premature CAD or other vascular disease. A history of myocardial infarction or…

…profoundly influences prognosis and therapeutic decision making. Structural Heart Disease (SHD): Accounting for approximately 90% of all VT presentations, SHD provides the macroscopic architectural abnormalities…

…diabetes mellitus Atherosclerotic cardiovascular events HF and atrial fibrillation Obesity therefore acts both as an independent cardiovascular risk factor and as a driver of hypertension…

…forces that drive coronary and cerebral perfusion, and ventilation of the lungs during cardiopulmonary resuscitation (CPR) differ substantially from normal circumstances. The purpose of CPR…

…Figure 1). Unipolar vs. bipolar pacing Pacemakers can utilize either a unipolar or bipolar mode of pacing (Figure 3). In bipolar pacing, the voltage difference…

…programming. The simplest pacemaker systems consist of a pulse generator and one lead, which is located either in the right atrium or the right ventricle…

…all clinical trials, epidemiological studies and mechanistic studies have been carried out in HFREF (heart failure with reduced ejection fraction) . Thus, our current knowledge of…

…all clinical trials, epidemiological studies and mechanistic studies have been carried out in HFREF (heart failure with reduced ejection fraction) . Thus, our current knowledge of…

…bleeding. Have high ischaemic risk. Do not have a high risk of major or life threatening bleeding. Extended treatment may also be considered in patie

…stabilized or slightly declined over the past two decades, the incidence of HFpEF continues to rise steeply [6] . This epidemiological shift is primarily driven by…

…linking). Concurrent activation of the coagulation cascade leads to thrombin generation and fibrin deposition, culminating in a partially or fully occlusive intraluminal thrombus [5] . ACS…

…Therapies : Consideration of endomyocardial biopsy or anti inflammatory therapies may be warranted in specific clinical contexts [4]. Reduction of Sympathetic Drive Modulating autonomic tone is…

…cardiovascular events (MACE), whereas BMI alone often fails to capture these specific pathological drivers. 5 Physiological Mechanisms of Cardioprotection: Direct vs. Weight Mediated The profound…

…cardiovascular societies, defines HF as a clinical syndrome corroborated by elevated natriuretic peptide levels and/or objective evidence of pulmonary or systemic congestion [3] . Within…

…left atrial enlargement, and abnormalities of diastolic filling. Mitral regurgitation may develop through papillary muscle displacement, annular dilatation, or both; progressive ventricular remodeling may also…