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ECG J wave syndromes: hypothermia, early repolarization, hypercalcemia & Brugada syndrome

…in Brugada syndrome Brugada syndrome is a rare channelopathy (an electrical disorder caused by mutations in cardiac ion channels) which predisposes the individual to syncope…

Chronic Heart Failure With Reduced Ejection Fraction: Four-Pillar Therapy

…arrhythmias, thyroid disease, iron deficiency and anaemia, kidney dysfunction, sleep disordered breathing, cancer related disease and cardiac amyloidosis among the relevant clinical settings or comorbidities…

Differential Diagnosis of Chest Pain: A Clinical Overview

…Malignancy: A history suggesting an autoimmune disorder or known malignancy may suggest specific, nonidiopathic etiologies [2]. Summary of Pain Characteristics The following table synthesizes the…

ECG changes due to electrolyte imbalance (disorder)

…of serious arrhythmias. This is possible because there is a correlation between the severity of electrolyte imbalance and the visible ECG changes. Specific electrolyte disorders…

Peripheral Artery Disease: Diagnosis, Ankle–Brachial Index and Risk Management

…adventitial disease and trauma. Atherosclerotic PAD is a manifestation of systemic arterial disease rather than an isolated disorder of the lower limbs. Patients frequently have…

Vasovagal Syncope: Diagnosis, Tilt Testing and Treatment

Arrhythmias and arrhythmology Cardiology Definition and Pathophysiology Vasovagal syncope represents the most common form of neurally mediated syncope (NMS), a disorder of autonomic reflexes. It…

🟠 QT Drugs: Drugs causing QT prolongation, torsade de pointes (TdP) and long QT syndrome (LQTS)

…Nielsen syndrome Romano Ward syndrome Idiopathic congenital long QT syndrome (LQTS) Metabolic disorders Hypokalemia Hypomagnesemia Hypocalcemia Starvation Anorexia nervosa Liquid protein diets Hypothyroidism Bradyarrhythmia Sinus…

Pulmonary Hypertension: Classification and Treatment Principles

Cardiology Respiratory medicine Definition and Pathophysiology Pulmonary hypertension (PH) is a heterogeneous pathophysiological disorder characterized primarily by elevation of pulmonary arterial pressure. It may arise…

Familial Hypercholesterolaemia: Diagnosis, Cascade Screening and Treatment

…clinical disease. HeFH affects approximately 1 in 250–300 people and is the most common inherited metabolic disorder associated with premature cardiovascular disease. Prevalence is…

Atherosclerosis: Pathogenesis from Fatty Streak to Plaque Rupture

…vasoconstriction, adhesion of circulating cells, inflammatory cell entry into the intima, and thrombus formation. Atherosclerosis is therefore not simply a disorder of lipid storage. Its…

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