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Familial and Genetic Screening in Premature Cardiovascular Disease

…cardiomyopathies and channelopathies. Nevertheless, apparently sporadic disease may result from: Incomplete penetrance of a variant inherited from a parent. A de novo variant. Less commonly…

Heart Failure With Mildly Reduced Ejection Fraction

…commonly male and younger than those with HFpEF and have a greater likelihood of coronary artery disease, which is present in approximately 50–60% of…

Hypertension: Causes, investigations, complications & treatment

…a multifactorial disease caused by a complex interplay between genes and environment. Industrialization and a Western lifestyle are strongly related to the development of hypertension…

🟠 Calculate CHADS-VASc Score and evaluate indication for anticoagulation

…No treatment Low No treatment High 1 Oral anticoagulation (warfarin or NOAK 1 is considered for male patients with a score of 1 or more…

Cardiovascular Risk in Women: Sex-Specific Factors

…treatment response and outcomes of cardiovascular disease. The biological differences between females and males arise partly from the chromosomal distinction between XX and XY individuals…

Atrial fibrillation: ECG, classification, causes, risk factors & management

…a progressive disease. Complications of atrial fibrillation and available treatments In multivariable models (i.e statistical models in which adjustment has been made for confounders…

PCSK9 Inhibitors: Indications, Efficacy and Access

…limb events (MALE), and improves walking distance. The role of PCSK9 inhibition in thoracic or abdominal aortic aneurysmal disease remains an emerging area of research…

Abdominal Aortic Aneurysm: Screening and Surveillance

…located below the renal arteries and are related to atherosclerotic disease. At least 90% of AAAs larger than 4 cm are associated with atherosclerotic pathology…

Ventricular fibrillation, pulseless electrical activity and sudden cardiac arrest

…cardiac disease. Moreover, the time limit (1 hour) is not absolute. Sudden cardiac death causes 7 million deaths annually worldwide. The most common cause of…

Aspirin in Primary Prevention: Current Recommendations

…with risk increasing particularly after 70 years Male sex Previous upper gastrointestinal disease Hepatic or renal disease Multiple cardiovascular risk factors Concomitant nonsteroidal anti inflammatory…

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