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Alcohol and Cardiovascular Disease

…associated with hypertension, coronary artery disease, arrhythmias, heart failure and alcohol related cardiomyopathy. The cardiovascular implications of lower alcohol intake remain controversial. Epidemiological studies have…

Acute Limb Ischaemia: Recognition and Urgent Management

…ischaemia (ALI) is an abrupt reduction in arterial perfusion of an upper or lower limb that causes tissue metabolic requirements to exceed available blood flow…

Ankle-brachial index (ABI)

…its lower edge about 2 cm above the tip of the malleolus. 3. Dorsalis pedis artery — the signal is sought on the dorsum of the…

The T-wave: physiology, variants and ECG features

…and symmetric. Their duration is short; they typically disappear within minutes after a total occlusion in a coronary artery occurs (then of course, the ST…

Smoking Cessation: Pharmacotherapy and Cardiovascular Benefit

…coronary syndrome Reinfarction reduced by approximately 30–40%; death reduced by approximately 35–45% Peripheral artery disease Lower risk of progression to chronic limb threat

ST-Elevation Myocardial Infarction Complicated by Cardiogenic Shock

…zone. Coronary Occlusion and Myocardial Injury STEMI generally results from abrupt reduction in coronary blood flow caused by thrombotic occlusion of a previously atherosclerotic artery…

Drug-Eluting Coronary Stents: Evolution, Evidence and Stent Choice

…procedural complexity, and the relative merits of PCI and coronary artery bypass grafting (CABG). Definition and Pathophysiology From balloon angioplasty to coronary stents Balloon angioplasty…

Levosimendan (Simdax, Simendan) in acute heart failure

…and (3) modulation of sarcolemmal and mitochondrial potassium ATP channels. Levosimendan alleviates heart failure symptoms, increases cardiac output, and lowers pulmonary artery pressure without increasing…

🟠 Enalaprilat

Enalaprilat Enalaprilat is rarely used in hypertensive crisis due to its slow onset, prolonged duration of effect, and significant individual variations in its effect. Drug…

🟠 Labetalol

…coronary artery disease since it does not increase heart rate, and reduces myocardial oxygen consumption. Time to onset of action: 5 minutes. Effects Lowers blood…

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