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Ischemic Cardiomyopathy: Myocardial Viability Assessment and Revascularization

…several overlapping processes: Recurrent or extensive MI with necrosis and scar formation Diffuse myocardial fibrosis Reversible ischemic dysfunction Chronic hypoperfusion with hibernating myocardium Post ischemic…

Percutaneous Coronary Intervention Versus Coronary Artery Bypass Grafting in Multivessel Coronary Artery Disease

…left ventricular dysfunction, peripheral vascular disease and other manifestations of diffuse atherosclerosis. Percutaneous coronary intervention (PCI) and coronary artery bypass grafting (CABG) are revascularization procedures…

Abscess incision and drainage

… cellulitis instead gives a diffuse oedematous picture without a demarcated fluid collection. Ultrasound also shows the depth of the cavity and its distance to vessels…

Coronary Anatomy and Segmental Classification for the Clinician

…risk balance of revascularization. Coronary angiography remains primarily an anatomical examination, whereas contemporary decision making increasingly combines anatomical imaging with functional assessment. A central practical…

No-Reflow Phenomenon During Percutaneous Coronary Intervention: Prevention and Treatment

…Large areas of jeopardized myocardium, severe baseline stenosis, multivessel coronary artery disease, and diffuse disease increase the likelihood of cardiovascular collapse when PCI fails or…

Periprocedural Myocardial Infarction After PCI and CABG

…coronary artery disease, or diffuse disease. No reflow represents impaired antegrade myocardial perfusion in the absence of a flow limiting epicardial stenosis. It is associated…

Refractory Angina: Options When Standard Therapy Fails

…2%–24% of patients with CAD. The pathophysiology of refractory angina is heterogeneous. In obstructive CAD, symptoms may result from extensive or diffuse epicardial disease…

Statin Intolerance and Statin-Associated Muscle Symptoms

…some form of statin therapy after systematic reassessment and rechallenge. The principal manifestation is statin associated muscle symptoms (SAMS). These range from diffuse myalgia with…

Cardiac amyloidosis

…and impaired ventricular relaxation [10]. There is also an increased risk of intracardiac thrombus and stroke or systemic embolization, even in patients in sinus rhythm…

Chest Pain in the Emergency Department: Diagnostic Pathways

…2–6% of patients discharged with presumed non ischaemic chest pain were subsequently found to have had an infarction. Pathophysiological Considerations The central pathophysiological concern…

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