…a large burden of hibernating myocardium. Evaluation and physical examination The assessment should establish three complementary features: The severity of LV dysfunction The extent and…

…Large areas of jeopardized myocardium, severe baseline stenosis, multivessel coronary artery disease, and diffuse disease increase the likelihood of cardiovascular collapse when PCI fails or…

…of viable myocardium supplied by the affected vessel and the adequacy of collateral circulation. Abrupt loss of flow may cause rapid deterioration when a large…

…and perirectal Often larger than it appears; risk of fistula Surgeon, often operative management Breast Cosmesis, milk ducts, malignancy differential Surgeon or mammography Sole of…

…some form of statin therapy after systematic reassessment and rechallenge. The principal manifestation is statin associated muscle symptoms (SAMS). These range from diffuse myalgia with…

…likely to affect flow because they supply a larger myocardial territory. The response of the coronary circulation reflects both epicardial stenosis and the coronary microcirculation…

…ventricular dysfunction, peripheral vascular disease and other manifestations of diffuse atherosclerosis. Percutaneous coronary intervention (PCI) and coronary artery bypass grafting (CABG) are revascularization procedures. Both…

…atherosclerosis is diffuse, leading to underestimation of the overall disease burden. Angiography also provides limited information about plaque composition, vulnerability and the risk of future…

…patients require a mechanism based assessment rather than reassurance based solely on the absence of obstructive CAD. Evaluation and Physical Examination Clinical assessment The asses

…A history of increasing frequency of hospitalizations and visits for heart failure without disease recognition in the 3 years preceding diagnosis is also a notable…