…or a large burden of hibernating myocardium. Evaluation and physical examination The assessment should establish three complementary features: The severity of LV dysfunction The extent…

…Large areas of jeopardized myocardium, severe baseline stenosis, multivessel coronary artery disease, and diffuse disease increase the likelihood of cardiovascular collapse when PCI fails or…

…coronary artery disease, or diffuse disease. No reflow represents impaired antegrade myocardial perfusion in the absence of a flow limiting epicardial stenosis. It is associated…

… cellulitis instead gives a diffuse oedematous picture without a demarcated fluid collection. Ultrasound also shows the depth of the cavity and its distance to vessels…

…diffuse myalgia with a normal CK and no functional impairment to myositis with muscle inflammation and elevated CK. Rhabdomyolysis is a rare, severe form of…

…are more likely to affect flow because they supply a larger myocardial territory. The response of the coronary circulation reflects both epicardial stenosis and the…

…left ventricular dysfunction, peripheral vascular disease and other manifestations of diffuse atherosclerosis. Percutaneous coronary intervention (PCI) and coronary artery bypass grafting (CABG) are revascularization procedures…

…atherosclerosis is diffuse, leading to underestimation of the overall disease burden. Angiography also provides limited information about plaque composition, vulnerability and the risk of future…

…despite multiple antianginal agents and prior revascularization procedures. In many patients, the burden is sufficiently severe to limit ordinary activities and substantially impair quality of…

…cell dyscrasia in which abnormal plasma cells produce misfolded immunoglobulin light chains [8, 19]. Light chains are directly toxic to cardiomyocytes, inducing the elaboration of…

…descriptor is diagnostic. The severity of pain also has limited discriminatory value. Features suggesting myocardial ischaemia Ischaemic discomfort commonly: Is substernal and diffuse. Is described…

…In the earliest stages of ischemia, this may manifest as tall, positive hyperacute T waves [15]. Profound ST elevation across multiple leads generally indicates very…

… concealed diffuse atherosclerosis; myocardial bridging; myocardial metabolic abnormalities; and abnormal pain perception in patients without demonstrable ischaemia. The absence of obstructive disease therefore does not…

…it requires a normally perfused reference territory. In diffuse coronary disease, balanced multivessel disease, or global impairment of microvascular vasodilation, regional differences may be underestimated…

…Contrast staining of the arterial wall with multiple lumens or radiolucent channels The classic appearance and usually readily recognized Type 2 Long, smooth, diffuse luminal…

…MI, diffuse microvascular dysfunction, or flow limiting epicardial stenoses), is the predominant cause, accounting for approximately 60% of HFrEF cases in Western populations [14] . Non…

…is the cardinal symptom of coronary artery disease. It occurs when the myocardium becomes ischemic. It is typically described as a diffuse pain over the…

…exposure. It is metabolically inert and diffuses freely across cell membranes, allowing for precise quantification of myocardial blood flow and assessment of coronary flow reserve…