…from several overlapping processes: Recurrent or extensive MI with necrosis and scar formation Diffuse myocardial fibrosis Reversible ischemic dysfunction Chronic hypoperfusion with hibernating myocardium Post…

…Large areas of jeopardized myocardium, severe baseline stenosis, multivessel coronary artery disease, and diffuse disease increase the likelihood of cardiovascular collapse when PCI fails or…

…by the affected vessel and the adequacy of collateral circulation. Abrupt loss of flow may cause rapid deterioration when a large myocardial territory is jeopardized…

…argue for the operating theatre rather than the emergency room: a very large or deep abscess, a markedly unwell patient with fever and systemic upset…

…Clinical presentation and symptoms Typical SAMS consists of: Symmetric muscle pain Muscle aching or soreness Weakness, often perceived or functional Predominant involvement of large proximal…

…preserved FFR with reduced CFR may indicate coronary microvascular dysfunction or diffuse epicardial disease. Concordantly normal FFR and CFR are associated with an excellent prognosis…

…ventricular dysfunction, peripheral vascular disease and other manifestations of diffuse atherosclerosis. Percutaneous coronary intervention (PCI) and coronary artery bypass grafting (CABG) are revascularization procedures. Both…

…when atherosclerosis is diffuse, leading to underestimation of the overall disease burden. Angiography also provides limited information about plaque composition, vulnerability and the risk of…

…survive with severe, diffuse CAD that is no longer amenable to additional mechanical revascularization. Despite treatment with antianginal drugs and PCI or CABG, daily or…

…immunoglobulin light chain (AL) amyloidosis and transthyretin (ATTR) amyloidosis [8, 15]. AL Amyloidosis: This is a plasma cell dyscrasia in which abnormal plasma cells produce…