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Poisoning: quick reference for antidotes and initial management

…substances weight, age, pregnancy and comorbidity renal and hepatic function regular medication and drug dependence epilepsy or previous seizures suicidal intent packaging, blister packs, photographs…

🟠 ATRIA (Anticoagulation and Risk Factors in Atrial Fibrillation) Bleeding Risk Score

…g/dL in women (3 points) Severe Renal Disease: Estimated glomerular filtration rate (eGFR) <30 mL/min or dialysis dependent (3 points) Age ≥75 years…

Sotalol: Initiation, QT Monitoring and Renal Dosing

…to sinus rhythm. Biomarkers and Laboratory Findings Renal function biomarkers are essential in the evaluation and ongoing management of patients on sotalol. Because the drug…

Left Ventricular Function

…Indeed, myocardial mechanics constitute a whole research field. Cardiac function is also dependent on circulatory, pulmonary, renal and neurohormonal factors. These factors, which influence cardiac…

Acute coronary syndrome: quick reference for loading doses and time targets

…2]. STEMI and other ECG patterns suggesting acute coronary occlusion are time dependent conditions. The decision on immediate reperfusion is based on symptoms, the ECG…

Leg ulcers — wound debridement and compression therapy

…pale Variable, often deep Pain Moderate, relieved by elevation Severe, worse on elevation, better when dependent Often painless (neuropathy) Surrounding skin Hyperpigmentation, oedema, lipodermatosclerosis, eczema…

Ivabradine: Indications, Dosing and Heart-Rate Targets

…portion of its transmembrane pore, ivabradine reduces the slope of diastolic depolarisation and produces a dose dependent reduction in sinus rate. Its principal therapeutic distinction…

Torsades de Pointes: Definition, Characteristics, and Management

…DI LQTS and DI TdP is drug dependent, ranging between 1% and 8% for Class III antiarrhythmic agents depending on the specific drug and dosage …

Cardiac Tamponade: Recognition and Pericardiocentesis

…with elevation of their diastolic pressures. Right sided filling becomes increasingly dependent on the fall in intrathoracic pressure during inspiration. The inspiratory increase in right…

Ejection fraction (EF): Physiology, Measurement & Clinical Evaluation

…be generated during exercise. Effect of preload and afterload on ejection fraction Ejection fraction is highly dependent on preload and afterload. A rapid increase in…

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