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Introduction to Coronary Artery Disease (Ischemic Heart Disease)

ECG Myocardial ischemia and infarction Coronary artery disease (ischemic heart disease) Coronary artery disease, which is synonymous with ischemic heart disease, is the most common…

Adenosine: Administration Technique, Dose Escalation and Precautions

…decreases the accumulation of cyclic adenosine monophosphate (cAMP), which in turn reduces the L type calcium current (Ica.L) and the pacemaker current (If) in…

Noradrenaline, Dobutamine and Levosimendan: Practical Infusion Use

…effects on alpha receptors. Stimulation of beta receptors increases inotropy and chronotropy by elevating intracellular cyclic adenosine monophosphate (cAMP) and calcium, as well as through…

Primary Aldosteronism: Screening and Management

…develop weakness, muscle cramps or, in severe cases, periodic paralysis. Nevertheless, many patients are normokalaemic and have no distinctive symptoms attributable to aldosterone excess. Cardiovascular…

Cardiac arrest due to electrolyte imbalance

…nausea, vomiting, muscle cramps, apathy, confusion, impaired reflexes. Severe <115 mmol/L Seizures, coma, respiratory arrest, brainstem herniation and death. Table 2. Grading of hyponatremia…

Nasogastric tube

…and a decongestant nasal spray if the nasal passage is narrow. A 50–60 mL catheter syringe, a collection bag or suction, and a clamp…

Pharmacologic agents in myocardial perfusion imaging

…effects. It inhibits phosphodiesterases, particularly PDE3 and PDE5, which break down cAMP and cGMP. It also inhibits the cellular reuptake of adenosine into endothelial cells…

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