…significant geographical variations. Roughly 25% of children with congenital heart disease require intervention during their first year of life ( Triedman et al ). According to the…

Cardiology Genetic and miscellaneous conditions Definition and classification Coronary anomalies are congenital abnormalities involving the origin, course, distribution, or termination of the coronary arteries. They…

Echocardiography Pulmonary (pulmonic) stenosis Pulmonary stenosis is virtually always a consequence of congenital heart disease. The stenosis can be fixed or dynamic, depending on the…

Echocardiography Tricuspid valve stenosis Tricuspid stenosis is a rare condition that may be caused by rheumatic valvular disease, congenital heart disease, Whipple’s disease, or…

…Qp) to systemic blood flow (Qs). This measurement is pivotal in diagnosing and managing congenital or acquired cardiac shunts, such as atrial septal defects (ASD…

…to cardiomyopathies, channelopathies, heritable aortopathies, selected congenital heart diseases, pulmonary arterial hypertension and thromboembolic disorders. Most recognised heritable cardiovascular conditions demonstrate autosomal dominant transmission, in…

…explained by coronary heart disease, hypertension, valvular disease or congenital heart disease. Cardiomyopathy leads to impaired cardiac function and heart failure. There are six main…

…are cysts and tumors of the pericardium, as well as congenital malformations leading to an incomplete or absent pericardium. In case of suspicion of pericardial…

…Medical conditions Category Condition Congenital conditions Jervell and Lange Nielsen syndrome Romano Ward syndrome Idiopathic congenital long QT syndrome (LQTS) Metabolic disorders Hypokalemia Hypomagnesemia Hypocalcemia…

…arrhythmias and therefore QT duration must always be assessed. QT prolongation may be congenital (due to genetic mutations) or acquired (secondary to medications, electrolyte disorders)…

…hypertension, left ventricular hypertrophy, left ventricular dysfunction, valve disease, coronary artery disease, cardiomyopathy, congestive heart failure, congenital heart disease, diabetes mellitus (both type 1 and…

…Marfan syndrome Takayasu's arteritis Iatrogenic (e.g complication of catheterization) Congenital dysplasia/aplasia of the pulmonary valve Idiopathic pulmonary artery dilation Pulmonary regurgitation results…

…echocardiography. Causes of right ventricular hypertrophy Lung disease (with increased pulmonary vascular resistance), congenital heart disease (transposition of the great arteries, pulmonary valve stenosis, atrial…

…This results in electrical instability which explains why ventricular tachycardia may progress to ventricular fibrillation. Left untreated, ventricular fibrillation leads to asystole and cardiac arrest…

…that results from long QT syndrome (LQTS). TdP occurs exclusively in individuals with LQTS (congenital or acquired). The VT is polymorphic with a gradual alteration…

…ventricular tachycardia (including torsades des pointes), ventricular fibrillation arrests and moderate left ventricular dysfunction. This patient died at age 17 years due to complications related…

…defined as stenosis of at least 70%, while a left main coronary stenosis of at least 50% is considered significant. These thresholds describe luminal narrowing…

…by elevation of pulmonary arterial pressure. It may arise from pulmonary vascular disease, left sided cardiac disease, chronic lung disease or hypoxia, chronic thromboembolic obstruction…

…pediatric patients, and young adults with congenital heart disease. Initiation Strategies Because of its ability to significantly prolong the QT interval and cause torsades de…

…that results from long QT syndrome (LQTS). TdP occurs exclusively in individuals with LQTS (congenital or acquired). The VT is polymorphic with a gradual alteration…

…supply from one coronary artery (Coronary arteries). Chronic myocardial ischemia may also lead to left ventricular dilation, which is referred to as ischemic cardiomyopathy (Dilated…

…mitral valve orifice. There are many causes of mitral stenosis, the most common of which are rheumatic heart disease, congenital malformations, radiation complications, metastases, myxoma…