…the most common of which are rheumatic heart disease, congenital malformations, radiation complications, metastases, myxoma, cardiac thrombi, etc (Table 1). Most causes of mitral stenosis…

…testing), and cardiac catheterization. Principles of management of congenital heart disease and GUCH Complex malformations often require intervention (surgical or catheter based intervention). In addition…

…pericardial effusion and tamponade. Less common are cysts and tumors of the pericardium, as well as congenital malformations leading to an incomplete or absent pericardium…

…artery and a cardiac chamber or vessel. Other congenital anomalies include anomalous origin of a coronary artery from the pulmonary artery and anomalous origin of…

…setting of pulmonary valve stenosis, the pressure in the right ventricle rises, which results in right ventricular hypertrophy. The valve is usually thickened and during…

…tricuspid stenosis. Yet, there is no consensus regarding grading of tricuspid stenosis severity. Tricuspid stenosis is visually characterized by thickened leaflets, with reduced motion and…

…quantify the ratio of pulmonary blood flow (Qp) to systemic blood flow (Qs). This measurement is pivotal in diagnosing and managing congenital or acquired cardiac…

…counselling and, where appropriate, molecular testing. The approach is particularly relevant to cardiomyopathies, channelopathies, heritable aortopathies, selected congenital heart diseases, pulmonary arterial hypertension and thromboembolic…

…congenital heart disease. Cardiomyopathy leads to impaired cardiac function and heart failure. There are six main types of cardiomyopathy: Hypertrophic cardiomyopathy (HCM) — This type of…

…broad spectrum hydroxamic acid based inhibitor of histone deacetylase... <a href="http://www.ncbi.nlm.nih.gov/pubmed/?term=Abexinostat+AND+(%22QT%22+OR+Torsad " PubMed…

…the vulnerability caused by marked local differences in repolarization. This article is part of the comprehensive chapter: How to read and interpret the normal ECG

…heart failure, congenital heart disease, diabetes mellitus (both type 1 and type 2), obesity, smoking, obstructive sleep apnea and chronic obstructive pulmonary disease (COPD). Moreover…

…The ventricle and RVOT (right ventricular outflow tract) become dilated, which further agravates the regurgitation. The proximal portion of the pulmonary artery may also be…

…with increased pulmonary vascular resistance), congenital heart disease (transposition of the great arteries, pulmonary valve stenosis, atrial septal defect, ventricular septal defect), tricuspid valve regurgitation…

…disorders , congenital heart disease and catecholamine induced ventricular tachycardia . The vast majority of patients with ventricular tachycardia either have coronary artery disease (ischemic heart disease)…

…individuals with LQTS (congenital or acquired). The VT is polymorphic with a gradual alteration in the QRS amplitude, often with twisting of the QRS complex…

…A, Lange Nielsen F. Congenital deaf mutism, functional heart disease with prolongation of the Q T interval and sudden death. Am Heart J 1957;54…

…malignant than anomalous origin of the right coronary artery. High risk anatomical features include: An interarterial course between the aorta and pulmonary artery A slit…

…studies of pulmonary arterial hypertension (PAH). The threshold is not absolute: patient phenotype, risk factors for heart failure with preserved ejection fraction, echocardiographic findings, and…

…and young adults with congenital heart disease. Initiation Strategies Because of its ability to significantly prolong the QT interval and cause torsades de pointes or…

…individuals with LQTS (congenital or acquired). The VT is polymorphic with a gradual alteration in the QRS amplitude, often with twisting of the QRS complex…

…imperfecta typically causes prolapse of P2 (Figure 1). Myocardial ischemia affecting the papillary muscles or the connected myocardium may cause mitral prolapse, and thus regurgitation…