…separate chapter discusses Long QT syndrome (LQTS). A complete list of drugs causing QT prolongation can be found here. Corrected QT intervals (QTc) can be…

…cases of congenital heart disease reach adulthood ( Mandalenakis et al ). The largest leap in survival has been observed among cases with the most complex malformations…

…or other non autosomal dominant mechanisms. Complex or multifactorial genetic architecture. The inheritance pattern affects the appropriate scope and duration of family surveillance. For example…

…trans thoracic echocardiography. Causes of right ventricular hypertrophy Lung disease (with increased pulmonary vascular resistance), congenital heart disease (transposition of the great arteries, pulmonary valve…

…occlusions of arteries in the brain, limbs or other organs. However, the increased risk in mortality is not completely explained by the increased risk of…

…LQTS (congenital or acquired). The VT is polymorphic with a gradual alteration in the QRS amplitude, often with twisting of the QRS complex around the…

…LQTS (congenital or acquired). The VT is polymorphic with a gradual alteration in the QRS amplitude, often with twisting of the QRS complex around the…

…artery is less common but more malignant than an anomalous right coronary artery. Anomalous origin of a coronary artery from the pulmonary artery can result…

Echocardiography Pulmonary (pulmonic) stenosis Pulmonary stenosis is virtually always a consequence of congenital heart disease. The stenosis can be fixed or dynamic, depending on the…

…or mechanical prostheses. The former is preferred due to the lower risk of thrombosis and evidence demonstrating long term durability (Filsoufi et al). Percutaneous interventions…

…quantify the ratio of pulmonary blood flow (Qp) to systemic blood flow (Qs). This measurement is pivotal in diagnosing and managing congenital or acquired cardiac…

…congenital heart disease. Cardiomyopathy leads to impaired cardiac function and heart failure. There are six main types of cardiomyopathy: Hypertrophic cardiomyopathy (HCM) — This type of…

…of these are acute pericarditis (perimyocarditis), constrictive pericarditis, pericardial effusion and tamponade. Less common are cysts and tumors of the pericardium, as well as congenital…

Info A comprehensive list of conditions and drugs that may prolong the QT interval, and cause torsade de pointes (TdP) and long QT syndrome (LQTS…

…of catheterization) Congenital dysplasia/aplasia of the pulmonary valve Idiopathic pulmonary artery dilation Pulmonary regurgitation results in right ventricular volume overload, which gradually causes right…

…disorders , congenital heart disease and catecholamine induced ventricular tachycardia . The vast majority of patients with ventricular tachycardia either have coronary artery disease (ischemic heart disease)…

…disease with prolongation of the Q T interval and sudden death. Am Heart J 1957;54:59 68. Brugada P, Brugada J. Right bundle branch…

…termination, congenital absence or hypoplasia. Anomalous aortic origin of a coronary artery from the opposite sinus of Valsalva is associated with increased sudden death risk…

…or multifactorial mechanisms PAH is a distinct and uncommon form of precapillary PH. It is defined haemodynamically by precapillary PH in the absence of CTEPH…

…and young adults with congenital heart disease. Initiation Strategies Because of its ability to significantly prolong the QT interval and cause torsades de pointes or…

…of mitral regurgitation. Table 1. Causes of mitral regurgitation Degeneration, prolapse DCM (dilated cardiomyopathy) Ischemic heart disease (coronary heart disease) Rheumatic valve disease Endocarditis Congenital…

…LCX or the right coronary artery (RCA). For details, refer to chapter The Coronary Arteries. Mitral valve disease A wide range of conditions may cause…