25 träffar

DrugHMG-CoA reductase inhibitor
Atorvastatin

…CoA reductase inhibitor High-intensity statin with a long half-life, allowing it to be taken at any time of day unlike simvastatin. Muscle complaints…

DrugHMG-CoA-reduktashämmare
🇸🇪 Rosuvastatin

Crestor Rosuvastatin Krka Rosuvastatin Sandoz HMG-CoA-reduktashämmare Den mest potenta statinen per milligram: 10 mg sänker LDL ungefär lika mycket som atorvastatin 20 mg…

DrugHMG-CoA-reduktashämmare
🇸🇪 Simvastatin

Zocord Simvastatin Krka HMG-CoA-reduktashämmare Den statin som byggde evidensen för sekundärprevention, men som i dag oftast får stå tillbaka för atorvastatin och rosuvastatin…

DrugInhaled corticosteroid in fixed combination with long-acting β₂-agonist
Budesonide/formoterol

Symbicort Turbuhaler Bufomix Easyhaler DuoResp Spiromax Inhaled corticosteroid in fixed combination with long-acting β₂-agonist Formoterol is the only long-acting β₂-agonist with…

Drugα- and β-agonist
Adrenaline

Adrenalin Stragen EpiPen Jext α- and β-agonist The only drug that reverses all components of anaphylaxis, and the cornerstone of cardiac arrest treatment. The…

DrugNatural penicillin for parenteral use
Benzylpenicillin

Bensylpenicillin Viatris Benzylpenicillin Panpharma Natural penicillin for parenteral use First-line treatment for community-acquired pneumonia and erysipelas, and the foundation of the narrow-spectrum…

DrugEndogenous purine nucleoside, AV-nodal blocking agent
Adenosine

…Adenocor Endogenous purine nucleoside, AV-nodal blocking agent First-line treatment for regular narrow-complex tachycardia when vagal manoeuvres have failed. Acts by blocking the…

DrugThiazide diuretic
Bendroflumethiazide

Salures Bendroflumetiazid Evolan Thiazide diuretic Inhibits the Na⁺/Cl⁻ cotransporter in the distal tubule and is the most commonly used thiazide diuretic for hypertension. The…

DrugNarrow-spectrum beta-lactam antibiotic
Phenoxymethylpenicillin (penicillin V)

…Tikacillin Fenoximetylpenicillin EQL Pharma Narrow-spectrum beta-lactam antibiotic The first-choice oral penicillin for the most common respiratory and skin infections in outpatient care…

DrugXanthine oxidase inhibitor
Allopurinol

…months require flare prophylaxis because falling urate levels themselves trigger attacks. Two features make this drug dangerous: the hypersensitivity syndrome and the combination with azathioprine.

DrugRecombinant tissue plasminogen activator (rt-PA)
Alteplase

…is weight-based, pulmonary embolism and myocardial infarction use a fixed 100 mg — and confusing them is the most common serious error. The short half…

DrugThird-generation cephalosporin
Cefotaxime

…and most Enterobacterales, with good CNS penetration — making this the standard choice for community-acquired bacterial meningitis and severe sepsis of unknown origin. The price…

DrugDirect thrombin inhibitor (factor IIa)
Dabigatran

…thrombin and the only one with a specific, rapidly acting antidote — idarucizumab achieves complete reversal within minutes, which weighs heavily in patients who may need…

DrugLow molecular weight heparin
Dalteparin

…difference between the prophylactic dose and the therapeutic dose is fourfold and is expressed in IU — confusing the two is the most common dosing error…

DrugLong-acting benzodiazepine with active metabolite
Diazepam

…As standing treatment it is something entirely different: the parent compound has a half-life of one to two days and the active metabolite desmethyldiazepam…

DrugBroad-spectrum tetracycline
Doxycycline

…and Borrelia. Near-complete oral absorption and a long half-life make once-daily dosing possible. It is the standard choice in pneumonia in penicillin…

DrugVascular-selective dihydropyridine calcium channel blocker
Felodipine

…making it combinable with beta-blockers. The price of pure vasodilatation is dependent oedema, which is dose-related and the most common reason for discontinuation…

DrugIndirect thrombin and factor Xa inhibitor via antithrombin
Heparin (unfractionated)

…can be measured in real time with APTT, and it can be neutralised completely with protamine within minutes. This is why unfractionated heparin is the…

DrugDirect-acting arteriolar vasodilator
Hydralazine

…unsuitable as first-line treatment in hypertensive crisis — but useful in pre-eclampsia and as afterload relief in combination with a nitrate and beta-blocker.

DrugSpecific antidote to dabigatran, humanised Fab fragment
Idarucizumab

…never lets go. The effect is immediate and complete: unbound dabigatran in plasma falls by over 99 per cent directly after the infusion. The specificity…

DrugNon-selective β₁- and β₂-agonist without alpha effect
Isoprenaline

…β₁-stimulation produces marked chronotropy and inotropy, while equally potent β₂-stimulation dilates the vessels — completely without alpha effect. The result is that heart rate…

DrugNon-selective α-adrenergic blocker
Phentolamine

…hour. A niche drug: catecholamine-induced hypertensive crisis — phaeochromocytoma, cocaine and amphetamine intoxication, MAO inhibitor crisis — and local treatment of skin necrosis after noradrenaline extravasation.

DrugMuscarinic receptor antagonist (vagolytic)
Atropine

…drug is ineffective in infranodal block. The effect comes within one minute and fades over an hour or so, making it a bridge to pacing…

DrugCalcium salt for intravenous membrane stabilisation and calcium supplementation
Calcium gluconate

…approximately one third as much elemental calcium per ml as calcium chloride, and that confusion is the most common dosing error in acute calcium treatment.