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🟠 HEMORR₂HAGES Bleeding Risk Score

…e.g., CYP2C9 variants) (1 point) E xcessive fall risk (1 point) S troke (1 point) HEMORR₂HAGES Score Risk category Incidence of major bleeding (per…

Short and long-term prognostication in cardiac arrest

…to explain why neuronal cell death begins within 5–6 minutes (Lipton et al). Survival in cardiac arrest is highly dependent on the initial rhythm…

Myocardial Ischemia & infarction: Cellular changes, ECG and symptoms

…cellular functions, such as contraction and relaxation. Increasing cardiac workload by increasing heart rate and contractility (i.e contractile force), results in increased metabolism. Cardiac…

ST-Elevation Myocardial Infarction (STEMI): Pathophysiology, Diagnosis, and Management

…compromises the endothelial barrier, upregulating the expression of vascular cell adhesion molecule 1 (VCAM 1) and intercellular adhesion molecule 1 (ICAM 1), and increasing the…

Endotracheal intubation

…a small chin, tumour, an irradiated neck E valuate 3 3 2 3 fingerbreadths of mouth opening, 3 fingerbreadths from chin to hyoid, 2 fingerbreadths…

Cardiac arrest in hyperthermia and malignant hyperthermia

…S, Smith JE, Gwyther R, Kirkman E. Closed chest compressions reduce survival in an animal model of hemorrhage induced traumatic cardiac arrest. Resuscitation 2019;140…

Care after return of spontaneous circulation (ROSC)

…the evidence is often conflicting. Many recommendations are therefore based on observational data, expert opinion, or extrapolation from other fields (e.g. sepsis research) or…

Diagnostic Criteria for Acute Myocardial Infarction: Cardiac troponins, ECG & Symptoms

…an atherosclerotic plaque may also release atherosclerotic debris downstream, causing microvascular embolization (i.e occluding smaller vessels downstream). The thrombosis causes occlusion of the artery…

Introduction to Cardiac Pacing and Devices: Pacemaker, ICD, CRT

…To coordinate these two tasks, the heart has an intrinsic pacemaker–i.e. the sinus node–and an electrical conduction system composed of specialized myocardial…

NSTEMI (Non-ST Elevation Myocardial Infarction) & Unstable Angina: Diagnosis, Criteria, ECG, Management

…in a reduction of coronary blood flow and this causes subendocardial ischemia (i.e ischemia that only affects the subendocardium). STEMI, on the other hand…

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Clinical ECG Interpretation

The ECG book is a comprehensive e-book, covering all aspects of clinical ECG interpretation, and will take you from cell to bedside.

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