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Pulmonary Hypertension: Classification and Treatment Principles

…disease or hypoxia, chronic thromboembolic obstruction, or a range of miscellaneous conditions. Because several mechanisms may coexist, diagnosis and classification must integrate haemodynamics with the…

CPAP and non-invasive ventilation (NIV)

…postoperative hypoxaemia. Hypoxaemic failure where high flow nasal oxygen is insufficient and the carbon dioxide is normal. Bilevel NIV: Acute exacerbation of COPD with respiratory…

Management of bradycardia (bradyarrhythmia)

…sleep ( Dickinson et al ). Pronounced sinus bradycardia is frequently associated with hypoxic episodes caused by obstructive sleep apnea. The following bradyarrhythmias are considered normal findings…

Acute exacerbation of COPD: quick reference

…severe airflow obstruction pH below 7.35 with raised pCO₂ Acute or acute on chronic hypercapnic respiratory failure Rapidly falling pH An urgent ventilatory problem…

Type 2 Myocardial Infarction: Mechanisms and Management

…respiratory failure with severe hypoxaemia, severe anaemia, and hypotension or shock. Conversely, mechanisms that increase myocardial oxygen demand include sustained tachyarrhythmia and severe hypertension, with…

Obesity and Cardiovascular Disease: Assessment and Treatment

…diabetes, dyslipidaemia and systemic inflammation. It is also associated with respiratory disorders, notably obstructive sleep apnoea (OSA) and obesity hypoventilation syndrome, which further increase cardiovascular…

ACE Inhibitor Cough and Angioedema: Practical Management

…medicine, widely utilized for the management of hypertension, chronic ischemic heart disease, heart failure with reduced ejection fraction (HFrEF), and post myocardial infarction (MI) care…

Constrictive pericarditis: definition, causes, diagnosis & echocardiography

…sided heart failure, which is explained by the fact that high pressure in the right atrium leads to a decrease in atrial filling. Respiratory variations…

Hyponatraemia: quick reference for work-up and correction

…example a Glasgow Coma Scale below 8 Vomiting together with clear neurological impairment Respiratory failure or respiratory arrest Clinical signs of raised intracranial pressure or…

Opioid therapy in severe pain

…morphine Morphine has an active renally excreted metabolite that causes late sedation and respiratory depression Marked liver failure A reduced dose of all of them…

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