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ACE Inhibitor Cough and Angioedema: Practical Management

…therapies in cardiovascular medicine, widely utilized for the management of hypertension, chronic ischemic heart disease, heart failure with reduced ejection fraction (HFrEF), and post myocardial…

Opioid therapy in severe pain

…for pain). An opioid is rarely the right choice in nociplastic or neuropathic pain, in chronic non cancer pain, or in headache. A failure to…

Urinary catheterisation

…Indications Acute urinary retention. Chronic urinary retention with renal impairment or a large residual volume. A need for accurate measurement of urine output in a…

Chronic Coronary Syndrome: Diagnosis and Initial Evaluation

…state. Patients may remain stable for prolonged periods, but chronic coronary disease can progress or destabilize abruptly, leading to an acute coronary syndrome (ACS). Clinical…

Chronic Heart Failure With Reduced Ejection Fraction: Four-Pillar Therapy

…and an LVEF below 40%. Signs may be absent in early disease or after effective treatment. HFrEF is commonly associated with structural and functional ventricular…

Chronic Kidney Disease as a Cardiovascular Risk Factor

Cardiology Nephrology Definition and pathophysiology Chronic kidney disease (CKD) is defined by abnormalities of renal structure or function that persist for more than 3 months…

Percutaneous Coronary Intervention for Chronic Total Occlusions: Indications and Outcomes

Myocardial ischemia and infarction Definition and pathophysiology A chronic total occlusion (CTO) is a complete or nearly complete coronary arterial obstruction that has persisted for…

ST-Elevation Myocardial Infarction (STEMI): Pathophysiology, Diagnosis, and Management

Cardiology Coronary Atherosclerosis Coronary atherosclerosis is a chronic, progressive, and highly complex lipid driven inflammatory disease of the arterial intima that serves as the fundamental…

Atherosclerosis: Pathogenesis from Fatty Streak to Plaque Rupture

Cardiology Myocardial ischemia and infarction Definition and pathophysiology Atherosclerosis is a chronic, inflammatory disease of the arterial wall in which lipid accumulation, vascular cell dysfunction…

Obesity and Cardiovascular Disease: Assessment and Treatment

Cardiology Endocrinology & metabolism Definition and pathophysiology Obesity is a chronic, relapsing and biologically complex disease characterized by excessive accumulation of adipose tissue. It is an…

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