…The genetic mechanisms underlying hypertrophic cardiomyopathy are complicated and some gene variants may only cause hypertrophy under certain loading conditions (i.e in the presence…

…through the AV node, resulting in increased AV block. Sinus node dysfunction can be caused by supraventricular tachyarrhythmias (e.g. atrial fibrillation). Typically, periods of…

…stress conditions, particularly in significant coronary artery stenosis. Stress can be induced pharmacologically with coronary vasodilatory agents or simulated hemodynamically through exercise or the use…

…for example certain phenoxy acid herbicides (2,4 D, MCPA) and methotrexate overdose. Tumour lysis syndrome appears as an indication in older protocols but is…

…do not already have a condition conferring sufficiently high cardiovascular risk. They should not be applied as the principal risk tool in people with: Documented…

…may coexist, and certain disease entities can span both categories; for example, acute heart failure may occur in the context of acute myocardial ischaemia, though…

…health care exposure and the risk of resistant organisms 0 to 60 min Empirical intravenous antibiotics in septic shock or in certain or highly likely…

…to chapter The Coronary Arteries. Mitral valve disease A wide range of conditions may cause mitral valve disease, which results in changes in the pressure…

…and certain targeted cancer treatments. Fever is not obligatory Hypothermia, new confusion, tachypnoea, hypotension, rigors, abdominal pain or a rapid deterioration in general condition may…

…C The most reliable in routine clinical practice Cockcroft–Gault Still used in certain dosing recommendations — it gives clearance, not GFR Iohexol clearance The reference…