…Cerebral / peripheral vascular disease. Cancer. Acute coronary syndromes cause symptoms already at rest. Stable ischemic heart disease does not cause symptoms at rest unless the…

…towards the penumbra zone (the outermost and less ischemic area), which may receive oxygen from collateral vessels. In cardiac arrest, there is no cerebral perfusion…

…generally indicates an intact brainstem and adequate cerebral perfusion, whereas fixed, dilated pupils can signal severe global ischemia or even herniation of the brain stem…

…and induces vasodilation in coronary, renal, cerebral and mesenteric vessels. Few Dopamine medium dose Cardiogenic shock Vasodilatory shock Heart failure (HF), acute Heart failure (HF…

…and induces vasodilation in coronary, renal, cerebral and mesenteric vessels. Few Dopamine medium dose Cardiogenic shock Vasodilatory shock Heart failure (HF), acute Heart failure (HF…

…follow up Main risk of management Overtreatment may impair autoregulation and cause ischemia Acute rapid reduction may cause harm without prognostic benefit Clinical Presentation and…

…victim's outcome: Neurological injury Myocardial dysfunction Systemic response to reperfusion and ischemia Effects of the underlying cause of cardiac arrest Neurological injuries may cause…

…and cerebral arteries. Ultrasound may reveal atherosclerotic plaques, thrombi, occlusions, and dissections. Stroke is subdivided into hemorrhagic stroke (13% of all cases) and ischemic stroke…

…examination are the initial components of assessment. The history should include: previous TIA or stroke; symptoms suggesting current or recent cerebral ischaemia; known CAD, PAD…

…drugs. Such treatment has not been shown to improve the prognosis and can cause hypotension, acute kidney injury, myocardial ischaemia or cerebral hypoperfusion. Pain, anxiety…

…increase the risk of stroke and other thromboembolic events. Subclinical cerebral injury may contribute to vascular dementia, and thromboembolism may affect organs other than the…

…phenotype or variant. Pathophysiology The precise mechanism of preeclampsia remains incompletely established. Proposed contributors include chronic uteroplacental ischaemia, an exaggerated maternal inflammatory response, and disturbed…

…Low dose dopamine stimulates D1 receptors and induces vasodilatation in the coronary, renal, cerebral and mesenteric vessels. Few Dopamine — intermediate dose Cardiogenic shock. Vasodilatory shock…

…malperfusion, myocardial ischaemia, heart failure, shock and cerebral or visceral malperfusion. Type B disease may produce rupture, renal, mesenteric or limb malperfusion, spinal cord ischaemia…

…established ASCVD, its potential reduction in non fatal myocardial infarction and ischaemic stroke must be weighed against clinically important gastrointestinal and intracranial bleeding. Evidence in…

CPR The forces that drive coronary and cerebral perfusion, and ventilation of the lungs during cardiopulmonary resuscitation (CPR) differ substantially from normal circumstances. The purpose…

…sodium chloride, whether the hyponatraemia is acute or chronic. The aim is to relieve the cerebral oedema quickly, not to normalise the plasma sodium. Chronic…

…rapidly with intravenous drugs. Restart or optimise oral treatment and ensure follow up. Rapid lowering can worsen cerebral, coronary and renal perfusion, particularly in patients…

…Intracranial pressure (ICP) < 22 mmHg The treatment threshold in traumatic brain injury Cerebral perfusion pressure (CPP) 60–70 mmHg CPP = MAP − ICP RASS…

…onset of action: 2 to 5 minutes Duration of action: 5 to 10 minutes. Adverse effects Headache (cerebral vasodilation). Tachycardia (due to reflex sympathetic activation)…

…g., vasovagal syncope) or with treatment (e.g., arrhythmias). Unconsciousness occurs within 10 seconds of cessation of cerebral blood flow. Agonal breathing : Deep, slow, irregular…

…arise from a range of injuries. Any trauma impairing ventilation or gas exchange can cause hypoxia. Such traumas include cerebral, facial, airway and thoracic injuries…

…dependent reduction in coronary and renal perfusion. • Dose dependent elevation of intracranial pressure (ICP) and reduction in cerebral blood flow. Caution • Used cautiously in patients…

…showing severe hypercholesterolaemia. A personal history of premature CAD, cerebral vascular disease or peripheral vascular disease. A family history of premature myocardial infarction, vascular disease…