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Sotalol: Initiation, QT Monitoring and Renal Dosing

Arrhythmias and arrhythmology Pharmacology & dosing Definition and Pathophysiology Sotalol is a nonselective beta adrenoceptor blocker devoid of intrinsic sympathomimetic activity that also prolongs cardiac repolarization…

Antianginal Therapy: Beta-Blockers, Calcium Channel Blockers, Nitrates, and Ranolazine

…CCS. General strategy For most patients, initial therapy consists of a beta blocker and/or a calcium channel blocker (CCB). If symptoms remain inadequately controlled…

🟠 1-2-3-LQTS Risk Calculator

…cardiac arrest, recurrent syncope despite beta blocker therapy, or markedly prolonged QT intervals—the implantation of an implantable cardioverter defibrillator (ICD) is recommended. ICDs provide…

🟠 1-2-3-LQTS Risk Calculator

…cardiac arrest, recurrent syncope despite beta blocker therapy, or markedly prolonged QT intervals—the implantation of an implantable cardioverter defibrillator (ICD) is recommended. ICDs provide…

Ivabradine: Indications, Dosing and Heart-Rate Targets

…70 beats/min; persistent symptoms despite evidence based therapy with an ACE inhibitor or ARNI, a beta blocker and a mineralocorticoid receptor antagonist. In this…

Drugs in the emergency setting

…must go home with an adrenaline auto injector and written instructions. Patients taking beta blockers may respond poorly to adrenaline. If there is no response…

🟠 Antiarrhythmic drugs in acute ventricular arrhythmias (ventricular tachycardia, ventricular fibrillation)

…Classification according to duration: Sustained VT : VT 30 seconds, or VT <30 seconds terminated by therapy. Non sustained VT (NSVT) : VT with ≥3 beats and…

Antiarrhythmic drugs in ventricular tachyarrhythmias

…Classification according to duration: Sustained VT : VT 30 seconds, or VT <30 seconds terminated by therapy. Non sustained VT (NSVT) : VT with ≥3 beats and…

🟠 Inotropes and Vasopressors

…and additionally severe hypertension (caution if patient on nonselective beta blockers). Dobutamine Cardiogenic shock Bradycardia (second line therapy) Stress testing (due to induced increase in…

Inotropes and Vasopressors: Doses, indications, contraindications and effects

…and additionally severe hypertension (caution if patient on nonselective beta blockers). Dobutamine Cardiogenic shock Bradycardia (second line therapy) Stress testing (due to induced increase in…

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