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Antianginal Therapy: Beta-Blockers, Calcium Channel Blockers, Nitrates, and Ranolazine

…Similarly, evidence for routine long term beta blocker therapy after uncomplicated acute coronary syndrome when LVEF is 40% is not definitive. Observational studies have yielded…

Sotalol: Initiation, QT Monitoring and Renal Dosing

Arrhythmias and arrhythmology Pharmacology & dosing Definition and Pathophysiology Sotalol is a nonselective beta adrenoceptor blocker devoid of intrinsic sympathomimetic activity that also prolongs cardiac repolarization…

🟠 1-2-3-LQTS Risk Calculator

…risk—such as those with a history of cardiac arrest, recurrent syncope despite beta blocker therapy, or markedly prolonged QT intervals—the implantation of an…

🟠 1-2-3-LQTS Risk Calculator

…risk—such as those with a history of cardiac arrest, recurrent syncope despite beta blocker therapy, or markedly prolonged QT intervals—the implantation of an…

Drugs in the emergency setting

…must go home with an adrenaline auto injector and written instructions. Patients taking beta blockers may respond poorly to adrenaline. If there is no response…

Ivabradine: Indications, Dosing and Heart-Rate Targets

…B. Every effort should be made to initiate and up titrate beta blocker therapy to guideline recommended or maximally tolerated doses before ivabradine is considered…

ECG changes caused by antiarrhythmic drugs, beta blockers & calcium channel blockers

…and treatment of life threatening ventricular tachyarrhythmias. Propafenone is usually not the first line therapy in this patient category. Prophylaxis and treatment of symptomatic paroxysmal…

Levosimendan (Simdax, Simendan) in acute heart failure

…without increasing myocardial oxygen consumption. The inotropic effect of levosimendan is not affected by the concurrent use of beta blockers. The vasodilating effect reduces preload…

Isoprenaline and Dopamine Infusions for Bradycardia

…process. A broad spectrum of pharmacologic agents can induce bradycardia or conduction disorders. These include beta blockers, non dihydropyridine calcium channel blockers, antiarrhythmic drugs (amiodarone…

Sinus node dysfunction (SND) and sick sinus syndrome (SSS)

…development of fibrosis) of the sinoatrial node. Myocardial ischemia/infarction. Perimyocarditis. Drug side effects (diltiazem, verapamil, beta blockers, digitalis, amiodarone, clonidine, procainamide). Hypoxia (hypoxemia) Hyperkalemia…

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