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Colchicine and Anti-inflammatory Therapy in Coronary Disease

…rather than lipid lowering. Other anti inflammatory strategies have produced less favourable results. Canakinumab, a monoclonal antibody directed against interleukin 1β, provided proof of…

🟠 TIMI Risk Score for NSTEMI and unstable Angina

All patients with NSTE ACS (NSTEMI or unstable angina) are treated similarly with respect to anti ischemic and anti thrombotic drugs. Management must, however, be…

Corticosteroids: quick reference for dose equivalents and stress dosing

…Two situations are often confused: replacement therapy in adrenal insufficiency (which must be increased under stress) and pharmacological anti inflammatory treatment (which must be tapered…

🟠 Aspirin (Acetylsalicylic acid)

…history of asthma, rhinitis, or urticaria triggered by: Acetylsalicylic acid (aspirin). Other non steroidal anti inflammatory drugs (NSAIDs). Other contraindications: Hemophilia. Thrombocytopenia. Active gastric or…

In-Stent Restenosis: Mechanisms and Treatment

…through intimal thickening. DES release antiproliferative and anti inflammatory agents from the stent surface and have substantially reduced this process compared with BMS. Neoatherosclerosis Neoatherosclerosis…

Post-Infarction Pericarditis and Dressler Syndrome

…cardiac tissue, the latent interval of several weeks, improvement with anti inflammatory treatment, and the tendency to recur all support an immunopathological mechanism. The precise…

Refractory Angina: Options When Standard Therapy Fails

…to established reversible myocardial ischaemia in either of two settings: Obstructive coronary artery disease (CAD) that cannot be controlled despite escalation of antianginal medical therapy…

Acute severe asthma in adults: quick reference

…drugs, and how many doses, has the patient taken? Is the patient on an inhaled corticosteroid or other anti inflammatory treatment? Previous intensive care, intubati

🟠 QT Drugs: Drugs causing QT prolongation, torsade de pointes (TdP) and long QT syndrome (LQTS)

…to the FDA in postmarketing studies. Anti androgen Cancer (Prostate) Abiraterone is an antiandrogen used in the treatment of prostate cancer. PubMed search Abiraterone ) DrugBank…

Aspirin in Primary Prevention: Current Recommendations

…Hepatic or renal disease Multiple cardiovascular risk factors Concomitant nonsteroidal anti inflammatory drugs Corticosteroid therapy Other antiplatelet or antithrombotic drugs Selective serotonin reuptake inhibitors Patient…

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