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Statin Intolerance and Statin-Associated Muscle Symptoms

…including modulation of inflammation, oxidative stress, endothelial function, plaque stability, thrombogenic responses and immune activity. Statin intolerance refers to adverse effects attributed to statin treatment…

Colchicine and Anti-inflammatory Therapy in Coronary Disease

…through activation of innate immune pathways, cytokine signalling and recruitment of inflammatory cells to vascular lesions. The interleukin 1β pathway, with downstream effects involving…

Reduction of dislocations

…shoulder dislocation, with an effect equivalent to sedation and fewer adverse effects Digital nerve block The standard in finger dislocation Procedural sedation Propofol, ketamine or…

🟠 Enalaprilat

…hours. Adverse effects Severe hypotension. Contraindications • Contraindicated in pregnancy, severe renal artery stenosis, severe hyperkalemia. • Avoid in acute heart failure and acute myocardial infarction. Enalaprilat…

🟠 Clevidipine

…egg), of which the maximum dose per 24 hours is 1000 mL. Adverse effects Headache. Nausea. Fever. Atrial fibrillation. Worsening of heart failure. Caution • Used…

🟠 Esmolol

…min. Maximum infusion dose: 300 μg/kg/min. Bolus doses of 300 μg/kg can be repeated during infusion. Adverse effects Flushing. Nausea…

🟠 Hydralazine

…hour. Adverse effects Tachycardia. Flushing. Headache. Angina pectoris. Caution Heart failure. Angina pectoris (ischemic heart disease). Hydralazine doses and administration in hypertension (hypertensive crisis/emergency).

Adenosine for tachyarrhythmias (AVNRT, AVRT, NCT)

…is not an established drug interaction. The half life of adenosine is 8 seconds. Adverse effects are therefore very brief. Indications Paroxysmal supraventricular tachycardia (PSVT…

Edrophonium test

…Observe pulse, blood pressure and muscle strength for a few minutes. 5. If the patient tolerates the test dose without troublesome adverse effects, give a…

Levosimendan (Simdax, Simendan) in acute heart failure

…ventricular and valvular function. Levosimendan drug is generally well tolerated. Severe adverse effects are less common. Levosimendan may be administered simultaneously with milrinone. The drugs…

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