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🟠 Hypertensive emergency (crisis) - Drugs, doses & management

…Any of the drugs listed below may be used to treat hypertensive emergencies. The desired time to action, contraindications and risk of adverse effects should…

Hypertensive emergency (crisis)

…Any of the drugs listed below may be used to treat hypertensive emergencies. The desired time to action, contraindications and risk of adverse effects should…

🟠 Clevidipine

…egg), of which the maximum dose per 24 hours is 1000 mL. Adverse effects Headache. Nausea. Fever. Atrial fibrillation. Worsening of heart failure. Caution • Used…

Colchicine and Anti-inflammatory Therapy in Coronary Disease

…cardiovascular adverse outcomes. Mechanisms of action Colchicine Colchicine appears to exert several anti inflammatory effects relevant to coronary disease: Reduction of inflammasome activation. Inhibition of…

Hypertensive crisis: drugs and doses

…antihypertensive drugs used in a hypertensive emergency. It summarises the mechanism of action, the onset, the duration of effect, the dosing, the adverse effects and…

Reduction of dislocations

…shoulder dislocation, with an effect equivalent to sedation and fewer adverse effects Digital nerve block The standard in finger dislocation Procedural sedation Propofol, ketamine or…

Digoxin - ECG changes, arrhythmias, conduction defects & treatment

…digoxin treatment. Adverse effects of digoxin The incidence of adverse drug reactions is high, owing to the narrow therapeutic index of the drug. Digoxin is…

Levosimendan (Simdax, Simendan) in acute heart failure

…Levosimendan drug is generally well tolerated. Severe adverse effects are less common. Levosimendan may be administered simultaneously with milrinone. The drugs can also be given…

Refractory Angina: Options When Standard Therapy Fails

…and effect on activities of daily living. Workload or exertion required to provoke symptoms. Response to current antianginal therapy. Adverse effects that restrict further drug…

PCSK9 Inhibitors: Indications, Efficacy and Access

…an effect not shared to the same extent by statins. Inclisiran Inclisiran is a liver targeted small interfering RNA. It promotes degradation of the messenger…

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