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Statin Intolerance and Statin-Associated Muscle Symptoms

…including modulation of inflammation, oxidative stress, endothelial function, plaque stability, thrombogenic responses and immune activity. Statin intolerance refers to adverse effects attributed to statin treatment…

Reduction of dislocations

…shoulder dislocation, with an effect equivalent to sedation and fewer adverse effects Digital nerve block The standard in finger dislocation Procedural sedation Propofol, ketamine or…

🟠 Enalaprilat

…variations in its effect. Drug Enalaprilat Brand names Vasotec IV ® Indications Hypertension and hypertensive emergency. Acute left ventricular failure. Mechanism of action Enalaprilat is…

🟠 Clevidipine

…egg), of which the maximum dose per 24 hours is 1000 mL. Adverse effects Headache. Nausea. Fever. Atrial fibrillation. Worsening of heart failure. Caution • Used…

🟠 Esmolol

…min. Maximum infusion dose: 300 μg/kg/min. Bolus doses of 300 μg/kg can be repeated during infusion. Adverse effects Flushing. Nausea…

🟠 Hydralazine

…the high risk of reflex sympathetic stimulation. Drug Hydralazine Brand names Apresoline ®, Bidil ® Mechanism of action • Induces arteriolar vasodilation. No effect on venous…

Adenosine for tachyarrhythmias (AVNRT, AVRT, NCT)

…or verapamil, although this is not an established drug interaction. The half life of adenosine is 8 seconds. Adverse effects are therefore very brief. Indications…

Edrophonium test

…test dose without troublesome adverse effects, give a further 8 mg intravenously , slowly. Rapid injection increases the risk of nicotinic effects with paradoxically increasing weakness…

Levosimendan (Simdax, Simendan) in acute heart failure

…Levosimendan drug is generally well tolerated. Severe adverse effects are less common. Levosimendan may be administered simultaneously with milrinone. The drugs can also be given…

Hypertensive crisis: drugs and doses

…antihypertensive drugs used in a hypertensive emergency. It summarises the mechanism of action, the onset, the duration of effect, the dosing, the adverse effects and…

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