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Amiodarone: Loading, Maintenance Dosing and Monitoring Schedule

…to Dosing Amiodarone exhibits highly variable and complex pharmacokinetics that profoundly influence its dosing strategies. The drug is slowly and incompletely absorbed after oral administration…

Cardiac arrest in hyperthermia and malignant hyperthermia

…a genetic mutation in the RYR1 receptor, resulting in persistent muscle contraction upon administration of halogenated anesthetic agents. As an idiosyncratic response to substances such…

Cardiac arrest during sepsis

…Causes of in hospital cardiac arrest and influence on outcome. Resuscitation 2012; 83:120611. Wang CH, Huang CH, Chang WT, et al. The effects of…

Adenosine: Administration Technique, Dose Escalation and Precautions

…receptors is responsible for the side effects of heart block, wheezing, and peripheral vasodilation, respectively. Pharmacokinetics and Administration Technique Adenosine is extensively and rapidly cleared…

🟠 Management of STEMI (ST-Elevation Acute Myocardial Infarction)

…completely relieved and ST segment elevation is completely normalized spontaneously or after nitroglycerin administration (provided there is no recurrence of symptoms or ST segment elevation)…

Physics of myocardial perfusion imaging (SPECT, PET): Radiotracers, perfusion, blood flow and viability

…the myocardial distribution of the tracers is fixed immediately after administration. Radiotracers with higher levels of redistribution can move from areas of higher concentration to…

The ECG in assessment of myocardial reperfusion

…reduction of the ST segment elevation by 50%) within 60 minutes after administration of thrombolysis. Otherwise, one must consider rescue PCI. For the purpose of…

🟠 Ticagrelor (Brilinta, Brilique)

Info Table 1 provides a summary of the indications, contraindications, dosage, administration, warnings, precautions, and other relevant information for the drug Ticagrelor . Table 1 Summary…

Urinary alkalinisation

…Heart failure, pulmonary oedema and other conditions with a high risk of fluid overload — a relative contraindication requiring invasive monitoring and slower administration. Significant metabolic…

🟠 Hydralazine

…® Mechanism of action • Induces arteriolar vasodilation. No effect on venous circulation. • May cause reflex sympathetic stimulation (can be counteracted with simultaneous administration of beta…

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