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🟠 Phentolamine

…Indications Hypertensive crisis. Mechanism of action Phentolamine is a non selective alpha adrenergic blocker. Phentolamine reduces blood pressure while increasing catecholamine activity. Effects Primarily causes…

Extracorporeal cardiopulmonary resuscitation (ECPR)

…compressions and defibrillation are paramount in restoring cardiac electrical activity, hence rhythm and contractility. Yet, in a significant number of cases, the rhythm is non…

Atrial Flutter: Mechanisms, ECG Recognition and Management

…and Pathophysiology Atrial flutter is defined by a macroreentrant atrial circuit, which manifests on the electrocardiogram (ECG) as organized, continuous atrial electrical activity. This activity…

ST-Elevation Myocardial Infarction: Diagnosis and Electrocardiographic Criteria

…exertion, it does not usually subside with cessation of activity, distinguishing it from angina pectoris. The location of the pain beneath the xiphoid and epigastrium…

Vasospastic (Prinzmetal) Angina: Provocation Testing and Treatment

…muscle sensitivity to calcium by inhibiting myosin phosphatase activity. Patients with VA are generally younger than those with atherosclerotic non ST elevation acute coronary syndromes…

Arrhythmias before and during cardiac arrest

…asystole. The tachyarrhythmias include ventricular fibrillation (VF) and pulseless ventricular tachycardia (VT). The bradyarrhythmias include all bradyarrhythmias, pulse less electrical activity (PEA), and asystole. Bradyarrhythmias…

Terminology of sudden cardiac arrest and resuscitation

…tachycardia). Non shockable rhythm : Cardiac rhythm that cannot be defibrillated or cardioverted. These rhythms include pulse less electrical activity (PEA), asystole, and bradycardia. No Flow…

Chronic Coronary Syndrome: Diagnosis and Initial Evaluation

…angina, angina or ischaemia with non obstructive coronary arteries (ANOCA/INOCA), post ACS or post revascularization states, and heart failure of ischaemic or cardiometabolic origin…

Colchicine and Anti-inflammatory Therapy in Coronary Disease

…Consequently, the decision to prescribe colchicine requires attention to the balance between reduction in ischaemic events and possible infectious or other non cardiovascular adverse outcomes…

Digoxin: Dosing, Therapeutic Range and Toxicity Management

…sinus baroreceptor activity and acts centrally and peripherally to enhance vagal tone. These sympatho inhibitory effects decrease serum norepinephrine levels, plasma renin levels, and potentially…

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