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Physical Activity Prescription for Cardiovascular Prevention

…Muscle strengthening exercise should additionally be performed on at least 2 days each week. Activities need not be undertaken in bouts of at least 10…

Ambulatory blood pressure monitoring and Holter ECG

…talk. Otherwise ordinary activities, including work. No showering or bathing. A diary of going to bed, getting up, medication intake, symptoms and any unusual activities…

Blood Pressure Targets in Older and Frail Adults

…potentially reversible. Management should therefore include consideration of treatable contributors, such as underlying comorbidities, supervised muscle strengthening physiotherapy, exercise, and coordination and balance training. Orthostatic…

Peripheral Artery Disease: Diagnosis, Ankle–Brachial Index and Risk Management

…or arteries supplying the limbs. In adults over 40 years of age, atherosclerosis is the predominant cause. Other mechanisms include thrombosis, embolism, vasculitis, fibromuscular dysplasia…

Refractory Angina: Options When Standard Therapy Fails

…In many patients, the burden is sufficiently severe to limit ordinary activities and substantially impair quality of life. The clinical impact should be assessed in…

🟠 Nitroprusside

…arterioles and veins via generation of cyclic GMP, which then activates calcium sensitive potassium channels in the cell membrane. Time to onset of action : 1…

Adenosine: Administration Technique, Dose Escalation and Precautions

…cells. Through the guanine nucleotide regulatory proteins Gi and Go, adenosine activates potassium channels (IK.Ach, K.Ado) in a manner analogous to acetylcholine. The…

🟠 Inotropes and Vasopressors

…Bradycardia (second line alternative) Medium dose : 3.0 10.0 μg/kg/min. + ++++ + +++++ Medium dose dopamine activates β1, releases norepinephrine and thus increases contractility…

🟠 Nitroglycerin

…and veins) via generation of cyclic GMP, which then activates calcium sensitive potassium channels in the cell membrane. Nitroglycerin is similar in action and pharmacokinetics…

Bempedoic Acid: Evidence and Clinical Use

…and high sensitivity C reactive protein (hsCRP). Bempedoic acid also activates adenosine monophosphate activated protein kinase, which regulates substrates involved in lipid metabolism and inflammatory…

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