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Physical Activity Prescription for Cardiovascular Prevention

Cardiology Clinical medicine Definition and Clinical Rationale Physical activity comprises bodily movement that increases energy expenditure, including walking, household tasks, active commuting and recreational activities…

Ambulatory blood pressure monitoring and Holter ECG

…talk. Otherwise ordinary activities, including work. No showering or bathing. A diary of going to bed, getting up, medication intake, symptoms and any unusual activities…

Blood Pressure Targets in Older and Frail Adults

…tests Ability to perform activities of daily living Cognitive status Risk of falls Symptoms or history suggesting orthostatic hypotension Multimorbidity Polypharmacy and overall therapeutic burden…

Peripheral Artery Disease: Diagnosis, Ankle–Brachial Index and Risk Management

…atherosclerosis is the predominant cause. Other mechanisms include thrombosis, embolism, vasculitis, fibromuscular dysplasia, arterial entrapment, cystic adventitial disease and trauma. Atherosclerotic PAD is a manifestation…

Refractory Angina: Options When Standard Therapy Fails

…despite multiple antianginal agents and prior revascularization procedures. In many patients, the burden is sufficiently severe to limit ordinary activities and substantially impair quality of…

🟠 Nitroprusside

…NO) that induces vasodilatation of both arterioles and veins via generation of cyclic GMP, which then activates calcium sensitive potassium channels in the cell membrane…

Adenosine: Administration Technique, Dose Escalation and Precautions

…the extracellular surface of cardiac cells. Through the guanine nucleotide regulatory proteins Gi and Go, adenosine activates potassium channels (IK.Ach, K.Ado) in a…

🟠 Inotropes and Vasopressors

…0 μg/kg/min. + ++++ + +++++ Medium dose dopamine activates β1, releases norepinephrine and thus increases contractility, chronotropy and mild increase in SVR. Ventricular arrhythmias Myocardial…

🟠 Nitroglycerin

…arterioles and veins) via generation of cyclic GMP, which then activates calcium sensitive potassium channels in the cell membrane. Nitroglycerin is similar in action and…

Bempedoic Acid: Evidence and Clinical Use

…B and high sensitivity C reactive protein (hsCRP). Bempedoic acid also activates adenosine monophosphate activated protein kinase, which regulates substrates involved in lipid metabolism and…

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