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Z17.421 Hormone receptor negative with human epidermal growth factor receptor 2 negative status
BackZ17Estrogen, and other hormones and factors receptor statusCategory6 →Z17.0Estrogen receptor positive status [ER+]CategoryZ17.1Estrogen receptor negative status [ER-]CategoryZ17.2Progesterone receptor statusCategory2 →Z17.21Progesterone receptor positive statusCategoryZ17.22Progesterone receptor negative statusCategoryZ17.3Human epidermal growth factor 2 receptorCategory2 →Z17.31Human epidermal growth factor receptor 2 positive statusCategoryZ17.32Human epidermal growth factor receptor 2 negative statusCategoryZ17.4Combined receptor statusCategory2 →Z17.41Hormone receptor positiveCategory2 →Z17.410Hormone receptor positive with human epidermal growth factor receptor 2 positive statusCategoryZ17.411Hormone receptor positive with human epidermal growth factor receptor 2 negative statusCategoryZ17.42Hormone receptor negativeCategory2 →Z17.420Hormone receptor negative with human epidermal growth factor receptor 2 positive statusCategoryZ17.421Hormone receptor negative with human epidermal growth factor receptor 2 negative statusCategory
CategoryCODABLE
Z17.421
Hormone receptor negative with human epidermal growth factor receptor 2 negative status
EXAMPLES
HR- with HER2-
TNBC
Triple negative breast cancer
TNBC
Triple negative breast cancer
- Chapter
- XXI · Factors influencing health status and contact with health services
- Section
- Z17
- Valid from
Source
CMS ICD-10-CM Tabular List, edition FY2026.