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R65.21 Severe sepsis with septic shock
BackR65Symptoms and signs specifically associated with systemic inflammation and infectionCategory2 →R65.1Systemic inflammatory response syndrome (SIRS) of non-infectious originCategory2 →R65.10Systemic inflammatory response syndrome (SIRS) of non-infectious origin without acute organ dysfunctionCategoryR65.11Systemic inflammatory response syndrome (SIRS) of non-infectious origin with acute organ dysfunctionCategoryR65.2Severe sepsisCategory2 →R65.20Severe sepsis without septic shockCategoryR65.21Severe sepsis with septic shockCategory
CategoryCODABLE
R65.21
Severe sepsis with septic shock
EXCLUDES
Excludes1: postprocedural septic shock (T81.12-)
- Chapter
- XVIII · Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
- Section
- R50-R69
- Valid from
Source
CMS ICD-10-CM Tabular List, edition FY2026.