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G90.81 Serotonin syndrome
BackG90Disorders of autonomic nervous systemCategory10 →G90.0Idiopathic peripheral autonomic neuropathyCategory2 →G90.01Carotid sinus syncopeCategoryG90.09Other idiopathic peripheral autonomic neuropathyCategoryG90.1Familial dysautonomia [Riley-Day]CategoryG90.2Horner's syndromeCategoryG90.3Multi-system degeneration of the autonomic nervous systemCategoryG90.4Autonomic dysreflexiaCategoryG90.5Complex regional pain syndrome I (CRPS I)Category4 →G90.50Complex regional pain syndrome I, unspecifiedCategoryG90.51Complex regional pain syndrome I of upper limbCategory4 →G90.511Complex regional pain syndrome I of right upper limbCategoryG90.512Complex regional pain syndrome I of left upper limbCategoryG90.513Complex regional pain syndrome I of upper limb, bilateralCategoryG90.519Complex regional pain syndrome I of unspecified upper limbCategoryG90.52Complex regional pain syndrome I of lower limbCategory4 →G90.521Complex regional pain syndrome I of right lower limbCategoryG90.522Complex regional pain syndrome I of left lower limbCategoryG90.523Complex regional pain syndrome I of lower limb, bilateralCategoryG90.529Complex regional pain syndrome I of unspecified lower limbCategoryG90.59Complex regional pain syndrome I of other specified siteCategoryG90.8Other disorders of autonomic nervous systemCategory2 →G90.81Serotonin syndromeCategoryG90.89Other disorders of autonomic nervous systemCategoryG90.9Disorder of the autonomic nervous system, unspecifiedCategoryG90.APostural orthostatic tachycardia syndrome [POTS]CategoryG90.BLMNB1-related autosomal dominant leukodystrophyCategory
CategoryCODABLE
G90.81
Serotonin syndrome
EXAMPLES
Serotonin toxicity
CODING RULE
Code first: poisoning due to drug or toxin, such as:
linezolid (T36.8X- with sixth character 1-4)
monoamine oxidase inhibitors (T43.1X with sixth character 1-4)
selective serotonin and norepinephrine reuptake inhibitors [SSNRI] (T43.21 with sixth character 1-4)
selective serotonin reuptake inhibitors [SSRI] (T43.22 with sixth character 1-4)
Use additional code: code for adverse effect, if applicable, to identify drug, such as:
linezolid (T36.8X5)
monoamine oxidase inhibitors (T43.1X5)
selective serotonin and norepinephrine reuptake inhibitors [SSNRI] (T43.215)
selective serotonin reuptake inhibitors [SSRI] (T43.225)
code, if applicable, to identify:
disseminated intravascular coagulation (D65)
hypertensive crisis (I16.-)
metabolic acidosis (E87.2-)
shock, not elsewhere classified (R57.-)
toxic encephalopathy (G92.-)
ventricular tachycardia (I47.2-)
linezolid (T36.8X- with sixth character 1-4)
monoamine oxidase inhibitors (T43.1X with sixth character 1-4)
selective serotonin and norepinephrine reuptake inhibitors [SSNRI] (T43.21 with sixth character 1-4)
selective serotonin reuptake inhibitors [SSRI] (T43.22 with sixth character 1-4)
Use additional code: code for adverse effect, if applicable, to identify drug, such as:
linezolid (T36.8X5)
monoamine oxidase inhibitors (T43.1X5)
selective serotonin and norepinephrine reuptake inhibitors [SSNRI] (T43.215)
selective serotonin reuptake inhibitors [SSRI] (T43.225)
code, if applicable, to identify:
disseminated intravascular coagulation (D65)
hypertensive crisis (I16.-)
metabolic acidosis (E87.2-)
shock, not elsewhere classified (R57.-)
toxic encephalopathy (G92.-)
ventricular tachycardia (I47.2-)
- Chapter
- VI · Diseases of the nervous system
- Section
- G89-G99
- Valid from
Source
CMS ICD-10-CM Tabular List, edition FY2026.