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Peripheral Artery Disease: Diagnosis, Ankle–Brachial Index and Risk Management

…much more common than upper extremity symptoms. The severity of symptoms should be described by their effect on walking distance, daily activities, work and independence…

Incretins in Cardiometabolic Medicine: Leveraging GLP-1, GIP, and Glucagon Receptor Agonism for Cardiovascular Risk Reduction

…considered extremely difficult across patient categories. However, the emergence of incretin based therapies, starting with glucagon like peptide 1 receptor agonists (GLP 1 RAs) and…

Clinical application of ECG in chest pain & acute myocardial infarction

…changes are extremely common in every population. For example, almost 80% of men display ST segment elevations that are not caused by ischemia and a…

Cardiac troponin I (TnI) and T (TnT): Interpretation and evaluation in acute coronary syndromes

…and a faster release kinetics. This may explain higher peak levels of cTnI compared with cTnT. Normal values (reference values) URL (upper reference limit) : The…

Diagnostic Criteria for Acute Myocardial Infarction: Cardiac troponins, ECG & Symptoms

…myocardial cells and therefore myocardial troponins should not be detected in the blood. It should be noted, however, that current troponin assays are extremely sensitive…

Upper gastrointestinal bleeding: quick reference

…commonest cause of upper gastrointestinal bleeding, but the differential diagnosis includes oesophagitis, gastritis, a Mallory Weiss tear, a Dieulafoy lesion, angiodysplasia, malignancy and an aortoenteric…

🟠 QTc Interval Calculator (Bazett’s, Fridericia’s, Hodge's and Framingham Formulas)

…male and female Adult, male Adult, female Normal <440 ms <430 ms <450 ms Upper limit 440–460 ms 430–450 ms 450–470 ms…

Acute Limb Ischaemia: Recognition and Urgent Management

Clinical medicine Emergency medicine Definition and pathophysiology Acute limb ischaemia (ALI) is an abrupt reduction in arterial perfusion of an upper or lower limb that…

🟠 Reference values for pediatric and neonatal ECG

…presented in the parenthesis). Values without confidence interval are simply the 98 th percentile (i.e the upper reference limit). Age <1 day 1–3…

Chest Pain in the Emergency Department: Diagnostic Pathways

…symptom. It includes pain, pressure, tightness, heaviness, burning, or discomfort in the chest and may extend to the arms, shoulders, neck, jaw, upper back, abdomen…

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