…and are best given orally when gut function is intact. Oral vancomycin (only for C. difficile) is likewise dosed independently of renal function. Require drug…

…65, and concomitant drug/alcohol use. Some studies suggest HAS BLED has comparable or slightly superior predictive capability for major bleeding compared to ATRIA. ORBIT…

…those of obstructive epicardial coronary disease or vasospastic angina. The clinical presentation is not sufficiently specific to identify the underlying mechanism. Microvascular, vasospastic, and obstructive…

…specific physical signs of CTO or a dedicated physical examination algorithm. Diagnostics Non invasive assessment of ischaemia and viability Objective evidence of ischaemia is important…

…following the successful ablation of typical flutter. Furthermore, typical flutter frequently emerges in patients undergoing pharmacological treatment for AF with class IC drugs or amiodarone…

…magnetic resonance imaging has demonstrated procedural injury in patients undergoing either procedure, and postprocedural cTnI elevation correlates with evidence of injury on cardiac magnetic resonance…

…months , irrespective of stent type. The preferred regimen is aspirin plus a potent P2Y12 inhibitor, usually prasugrel or ticagrelor. In patients undergoing PCI for ACS…

…patients with NSTE ACS undergoing angiography, approximately 10% have no critical epicardial stenosis. In some of these patients, microvascular obstruction or epicardial spasm may account…

…flow and the concentration of filtered substances along the nephron as water is reabsorbed. Nephrotoxic injury may involve the tubules, interstitium, renal vasculature or collecting…

…syndrome, stress testing may be considered after at least 24 hours of stabilization, provided that active ischaemia and haemodynamic or electrical instability are absent. A…