…only when related to one another. A low blood pressure may be due to low flow, low vascular tone or both, and the appropriate action…

…Transfusion restores circulating volume, oxygen transport and haemostatic capacity, but it cannot compensate for an uncontrolled source of bleeding. Minimise the time to surgery, endoscopy…

…translocates to the nucleus and induces expression of aldosterone responsive genes. Although the kidney is a major target—where MR activation promotes sodium transport—MRs…

…infarct size and preserving myocardial function. The benefit of reperfusion is strongly time dependent. The interval from symptom onset to reperfusion is determined by patient…

…infarct size. The extent of myocardial injury is strongly influenced by total ischaemic time. This interval includes: The time from symptom onset to recognition and…

…parallel with drug treatment and transport planning [1,5]. Symptom duration Under 12 hours: reperfusion is indicated in persisting STEMI. 12 to 48 hours: primary…

…up stroke or a late time window: perform advanced imaging according to the local protocol. 11. Document weight, agent, dose, time of the bolus and…

…than 18 mg are unlikely to revert a tachycardia and should not be used. Specific dosing adjustments are required in certain patient populations: Pediatric patients…

…when a patient is unable to tolerate any statin regimen. The treatment sequence for patients with chronic coronary syndrome is: Lifestyle intervention and a maximally…

…inflammation and fibrosis Reduction in body weight and haemoglobin A1c Increased uricosuria, with plasma uric acid reduction of approximately 10% to 15% Possible effects on…